<p>Marine bacteria represent a prolific source of structurally diverse and pharmacologically potent natural products, many of which exhibit promising anticancer properties. This bibliometric review systematically maps the landscape of marine bacteria-derived anticancer research, integrating insights from structural elucidation, bioactivity screening, and genomic exploration. Advanced analytical techniques such as nuclear magnetic resonance spectroscopy, mass spectrometry, and X-ray crystallography have enabled the identification of novel compounds with cytotoxic activity, while <i>in vitro</i> assays and <i>in silico</i> modeling have accelerated pharmacological profiling and mechanism-of-action studies. Concurrently, molecular tools including 16S rRNA sequencing, metagenomics, and genome mining have expanded our understanding of marine microbial diversity and biosynthetic gene clusters, revealing underexplored taxa with therapeutic potential. Synthetic biology and biosynthetic pathway engineering further enhance compound accessibility, addressing limitations in natural extraction yields. Moreover, overlapping mechanisms of action present an opportunity to simultaneously assess cytotoxic, antifungal, antimicrobial, and antioxidant activities, enabling the identification of multifunctional compounds with broad therapeutic potential. By combining bibliometric analysis with thematic synthesis, this study highlights emerging trends, key contributors, and future directions in marine bacterial anticancer research, underscoring the importance of interdisciplinary approaches in unlocking the pharmaceutical potential of marine microbiomes.</p> Graphical Abstract <p></p>