In this study, we introduce the notion of a higher-order strongly E-convex function of order \(\varvec{\sigma }\) as a generalization of the E-convex function and higher-order strongly convex function. We address nonconvex multiobjective fractional programming problems involving E-differentiable functions \(\varvec{(MFP_E)}\) . We establish E-Karush-Kuhn-Tucker sufficient optimality conditions for nonsmooth vector optimization problems under higher-order E-convexity hypothesis. Further, we formulate a multiobjective Schaible-type dual problem involving E-differentiable functions \(\varvec{(MSD_E)}\) for \(\varvec{(MFP_E)}\) and establish duality results between \(\varvec{(MFP_E)}\) and corresponding \(\varvec{(MSD_E)}\) under the assumption of higher-order strongly E-convexity hypothesis.