<p>This paper presents the development of a pedagogical framework for Agile-Blended learning, a novel technology-mediated pedagogical approach grounded in constructivist learning theories. It provides a detailed account of five relevant learning theories — Dewey (1938), Bruner (1966), Vygotsky (1978), Anderson (2008), and Harasim (2012) — to establish a theoretical foundation for Agile-Blended learning. Based on the core features of these theories, a pedagogical framework is proposed to support the implementation of Agile-Blended learning. This framework encompasses four key principles: adaptability, independence, engagement, and the application of information technology. These principles are interrelated and form a cohesive whole, guiding the implementation of effective teaching and learning practices. Future research directions related to Agile-Blended learning based on this framework are also discussed.</p>