Purpose <p>Endoscopic injection of bulking agents has become the preferred option in the management of persistent Paediatric vesicoureteric reflux (VUR). Our aim was to evaluate the efficacy of endoscopic management and identify the effectiveness of various injection techniques used in our institution.</p> Methods <p>We conducted a retrospective review of all patients who underwent endoscopic management of VUR at our institution from January 2000 to March 2023. Relevant procedure codes and keywords were used to identify cases from electronic operation records. The primary bulking agent used was Deflux, with Subureteric Injection (STING) being the most commonly performed injection technique.</p> Results <p>A total of 63 renal units in 49 patients underwent 73 endoscopic procedures. The average age at the time of intervention was 5.06&#xa0;years, with females predominating. More than half the patients had unilateral disease, and 54% had dilating reflux. The mean follow-up period was 66.2&#xa0;months. Symptom resolution was achieved in 86% of patients after their first injection. One patient required ureteric re-implantation due to non-resolution and worsening renal function, and two patients with persistent reflux were transitioned to adult services during follow-up.</p> Conclusions <p>Endoscopic injection of bulking agents at the vesicoureteral junction is an effective and minimally invasive intervention for managing VUR. All injection techniques demonstrated comparable efficacy in achieving symptom control, however, larger double blind multicenter trials are warranted to validate these findings.</p>