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<p><i>Satyrium nepalense</i> D. Don belonging to the family Orchidaceae is a terrestrial herb, well known for its medicinal values since ancient times. In traditional medicine, the tubers of this species have been extensively used as aphrodisiac and to mitigate various fevers.&#xa0;The objective of the present study was to investigate the bioactive compounds of <i>S. nepalense</i> using its tubers with gas chromatography and mass spectroscopy analysis (GC–MS). During the present study, chromatogram analysis of the methanolic tuber extract showed the presence of thirty two compounds in which 2-Amino-3-(3,4-dimethoxyphenyl) propanoic acid (58.00%), Hexadecanoic acid, 2-hydroxy-1-(hydroxymethyl) ethyl ester (21.64%), Ethanone, 2,2-dimethoxy-1,2-diphenyl- (8.41%), 9,19-Cyclolanost-24-en-3-ol, (3β)- (1.35%) were found to be prime compounds with known bioactivities such as antibacterial, antmicrobial, antiinflammatory, and antioxidant. The current study confirmed that the tubers of <i>S. nepalense</i> contain significant natural chemical compounds, validating its traditional use in various pharmacological activities.</p>

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Gc–Ms profiling of bioactive compounds in Satyrium nepalense D. Don: unlocking its potential for herbal medicine

  • 期刊论文

  • 发表日期：

    2025年11月13日

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  • Anamika Kumari,
  • Promila Pathak

摘要

Satyrium nepalense D. Don belonging to the family Orchidaceae is a terrestrial herb, well known for its medicinal values since ancient times. In traditional medicine, the tubers of this species have been extensively used as aphrodisiac and to mitigate various fevers. The objective of the present study was to investigate the bioactive compounds of S. nepalense using its tubers with gas chromatography and mass spectroscopy analysis (GC–MS). During the present study, chromatogram analysis of the methanolic tuber extract showed the presence of thirty two compounds in which 2-Amino-3-(3,4-dimethoxyphenyl) propanoic acid (58.00%), Hexadecanoic acid, 2-hydroxy-1-(hydroxymethyl) ethyl ester (21.64%), Ethanone, 2,2-dimethoxy-1,2-diphenyl- (8.41%), 9,19-Cyclolanost-24-en-3-ol, (3β)- (1.35%) were found to be prime compounds with known bioactivities such as antibacterial, antmicrobial, antiinflammatory, and antioxidant. The current study confirmed that the tubers of S. nepalense contain significant natural chemical compounds, validating its traditional use in various pharmacological activities.