Scholarlink

<p>The purpose of this study is to examine the phytochemical constituents, antioxidant capacity, and antibacterial activity of methanolic leaf extracts from <i>Dendrobium “Sonia Earsakul”</i> and <i>Dendrobium “Singapore White</i>,<i>”</i> two extensively grown but little-studied <i>Dendrobium</i> hybrids. In order to support their pharmacological significance and conservation, the goal is to evaluate their bioactive ingredients and validate their therapeutic potential. Qualitative phytochemical screening, agar well diffusion and MIC assays for antibacterial assessment, FRAP assay for antioxidant activity, FTIR analysis for functional group identification and Liquid Chromatography Mass Spectrometry (LC-MS) profiling were used to find key bioactive components using LC MS spectrum. Alkaloids, flavonoids, phenols, and steroids were detected by phytochemical screening, indicating potential medical use. According to antibacterial tests, <i>Dendrobium “Sonia Earsakul”</i> was more effective against <i>Escherichia coli</i> (MIC = 25&#xa0;mg/ml) than <i>Dendrobium “Singapore White”</i> which efficiently inhibited <i>Staphylococcus aureus</i> (MIC = 12.5&#xa0;mg/ml). Strong antioxidant activity was demonstrated by FRAP research in both species, but especially in <i>Dendrobium “Sonia Earsakul”</i>. Functional groups such -OH, -NH, C = O, and C-O were validated by FTIR, showing molecules with antibacterial and antioxidant activity. LC-MS analysis showed unique chemical profiles. <i>Sonia Earsakul</i> included hesperidin, rutin, soyasaponins, and derivatives of quercetin, while <i>Singapore White</i> was rich in isorhamnetin-3-glucoside, ginsenoside Rg1, and sphingomyelin, highlighting its adaptogenic and neuroprotective qualities. Strong bioactive compounds found in these <i>Dendrobium</i> hybrids validate their ethnomedical significance and potential use in the pharmaceutical and cosmetic industries. They also suggest that these hybrids may be used to develop natural antioxidants and alternative antimicrobial agents. Additionally, because these.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Phytochemical constituents, antioxidant and antibacterial activities of two Dendrobium hybrids

  • 期刊论文

  • 发表日期：

    2025年8月15日

查看全文
  • Nisruti Anuja Behura,
  • Naga Jogayya Kothakota

摘要

The purpose of this study is to examine the phytochemical constituents, antioxidant capacity, and antibacterial activity of methanolic leaf extracts from Dendrobium “Sonia Earsakul” and Dendrobium “Singapore White,” two extensively grown but little-studied Dendrobium hybrids. In order to support their pharmacological significance and conservation, the goal is to evaluate their bioactive ingredients and validate their therapeutic potential. Qualitative phytochemical screening, agar well diffusion and MIC assays for antibacterial assessment, FRAP assay for antioxidant activity, FTIR analysis for functional group identification and Liquid Chromatography Mass Spectrometry (LC-MS) profiling were used to find key bioactive components using LC MS spectrum. Alkaloids, flavonoids, phenols, and steroids were detected by phytochemical screening, indicating potential medical use. According to antibacterial tests, Dendrobium “Sonia Earsakul” was more effective against Escherichia coli (MIC = 25 mg/ml) than Dendrobium “Singapore White” which efficiently inhibited Staphylococcus aureus (MIC = 12.5 mg/ml). Strong antioxidant activity was demonstrated by FRAP research in both species, but especially in Dendrobium “Sonia Earsakul”. Functional groups such -OH, -NH, C = O, and C-O were validated by FTIR, showing molecules with antibacterial and antioxidant activity. LC-MS analysis showed unique chemical profiles. Sonia Earsakul included hesperidin, rutin, soyasaponins, and derivatives of quercetin, while Singapore White was rich in isorhamnetin-3-glucoside, ginsenoside Rg1, and sphingomyelin, highlighting its adaptogenic and neuroprotective qualities. Strong bioactive compounds found in these Dendrobium hybrids validate their ethnomedical significance and potential use in the pharmaceutical and cosmetic industries. They also suggest that these hybrids may be used to develop natural antioxidants and alternative antimicrobial agents. Additionally, because these.