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<p>Silver nanoparticles (AgNPs) were biosynthesized using an aqueous extract of <i>Inula viscosa</i> leaves. FTIR analysis indicated that the extract contains functional groups that aid in the reduction and stabilization of AgNPs. XRD confirmed the crystalline structure and an average size of 17.93&#xa0;nm, with the presence of silver oxide. SEM and TEM analyses revealed spherical AgNPs sized between 25 and 50&#xa0;nm. EDX analysis showed that the AgNPs are composed of 58.27% silver, along with traces of oxygen, carbon, chlorine, sodium, and sulfur. These findings suggest that <i>I. viscosa</i> extract is an effective medium for AgNP synthesis. The current study also explored the biological properties of the synthesized AgNPs, revealing significant antibacterial, antioxidant, and anti-inflammatory activities. The AgNPs exhibited notable anti-radical activity with an IC50 of 0.1815&#xa0;mg/ml for DPPH degradation and an 87% inhibition of red blood cell hemolysis, comparable to Diclofenac. These results validate the traditional use of <i>I. viscosa</i> leaves for AgNP biosynthesis and highlight their potential for various applications in antimicrobial, antioxidant, and anti-inflammatory fields.</p>

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An investigation of the biological properties of Inula viscosa (L.) extracts and their biosynthesis of silver nanoparticles

  • 期刊论文

  • 发表日期：

    2025年8月19日

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  • Fatima Zohra Yousfi,
  • Bennabi Farid,
  • Moussi Fatna,
  • Khane Yasmine,
  • Mohamedi Mohamed Walid,
  • Belarbi Lahcen,
  • Boukraa Djamila,
  • Rahmani Khaled,
  • Khalfa Ali,
  • Abdelkader Nebatti Ech-Chergui,
  • Zoukel Abdelhalim

摘要

Silver nanoparticles (AgNPs) were biosynthesized using an aqueous extract of Inula viscosa leaves. FTIR analysis indicated that the extract contains functional groups that aid in the reduction and stabilization of AgNPs. XRD confirmed the crystalline structure and an average size of 17.93 nm, with the presence of silver oxide. SEM and TEM analyses revealed spherical AgNPs sized between 25 and 50 nm. EDX analysis showed that the AgNPs are composed of 58.27% silver, along with traces of oxygen, carbon, chlorine, sodium, and sulfur. These findings suggest that I. viscosa extract is an effective medium for AgNP synthesis. The current study also explored the biological properties of the synthesized AgNPs, revealing significant antibacterial, antioxidant, and anti-inflammatory activities. The AgNPs exhibited notable anti-radical activity with an IC50 of 0.1815 mg/ml for DPPH degradation and an 87% inhibition of red blood cell hemolysis, comparable to Diclofenac. These results validate the traditional use of I. viscosa leaves for AgNP biosynthesis and highlight their potential for various applications in antimicrobial, antioxidant, and anti-inflammatory fields.