<p>Acid-triggered fluidization separation is a novel technology for separating carbonate minerals (such as calcite) from non-carbonate minerals. CO₂ bubbles released by the reaction of calcite with acids can reduce the apparent specific gravity of calcite particles, thereby facilitating the density-based separation of calcite from other minerals. However, generated CO₂ bubbles typically undergo rapid desorption from the calcite surface, leading to an insufficient separation time. In this study, the phenomenon and mechanism by which sodium dodecyl sulfonate (SDS) mitigates the desorption of CO₂ bubbles from calcite surfaces were investigated using a high-speed camera, sedimentation tests, Fourier-transform infrared spectroscopy, and contact angle measurements. The results showed that SDS effectively increased the residence time of CO₂ bubbles on the calcite surface, improved the bubble size uniformity, and prolonged the duration of the low apparent specific gravity of the calcite particles. The settling test showed that SDS effectively prolonged the settling time of the calcite particles in the presence of 300&#xa0;mg/L SDS. During the separation of calcite and fluorite in a sulfuric acid solution in a teetered bed separator (TBS sorting), SDS increased the grade of the fluorite concentrate from approximately 80% to more than 95%. This can be attributed to the adsorption of SDS on the calcite surface, which enhances the hydrophobicity of the treated calcite surface. SDS treatment has good application potential for separating carbonate and noncarbonate minerals in the acid solution of TBS sorting.</p>