<p>Consequences of poor mental health in the workplace are well documented, but mental health research specific to the mining industry remains scarce, especially in Canada. Findings are nonetheless compelling, as they seem to reflect higher rates of mental health-related symptoms among mining workers. The objective of this paper is to determine the symptom prevalence of stress, anxiety, and depression among a sample of Canadian mining workers and to identify demographic, psychosocial, and health-related, and work-related factors associated with stress, anxiety, and depression for these workers. 2224 mining workers across 25 worksites at one company in Ontario, Canada completed a self-reported questionnaire. The prevalence of depression symptoms (12.5%) and anxiety (5.9%) in this sample was found to be higher than in the working-age Canadian population, and multiple regression analyses revealed many shared predictors for stress, anxiety, and depression symptoms. The demographic, psychosocial and health-related predictors can be classified into four main categories: (1) individual characteristics, (2) interpersonal relationships, (3) lifestyle, and (4) the overlap between physical and mental health. Work-related predictors were also grouped into four categories: (1) work schedule and demands, (2) effort-reward imbalance and recognition and reward, (3) job insecurity and job satisfaction, and (4) the physical and psychological work environment. The findings illustrate the importance of recognizing the multidimensionality of health: mental health problems are undoubtedly the result of a number of interrelated factors, which include mental, physical, and social components, in addition to demographic and workplace-specific factors.</p>