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<p>This study explores the efficient and selective hydrazinolysis of pyranopyrazole derivatives through phenylhydrazine under mild conditions. The reaction provides a facile approach to ring cleavage <i>via</i> a new mild protocol and a catalyst-free environment, yielding hydrazone products. Structural characterization was performed using FTIR, <sup>1</sup>H and <sup>13</sup>C NMR analyses, confirming the transformation. The findings elaborated mechanistic insights into pyranopyrazole transformations in the presence of phenylhydrazine, to contribute to heterocyclic chemistry.</p>

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Efficient and selective hydrazinolysis of pyranopyrazole derivatives using phenylhydrazine

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年4月20日

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  • Saba Farooq,
  • Zainab Ngaini

摘要

This study explores the efficient and selective hydrazinolysis of pyranopyrazole derivatives through phenylhydrazine under mild conditions. The reaction provides a facile approach to ring cleavage via a new mild protocol and a catalyst-free environment, yielding hydrazone products. Structural characterization was performed using FTIR, 1H and 13C NMR analyses, confirming the transformation. The findings elaborated mechanistic insights into pyranopyrazole transformations in the presence of phenylhydrazine, to contribute to heterocyclic chemistry.