Introduction <p>Aberrant right subclavian artery (ARSA), also named “arteria lusoria”, is a congenital, usually asymptomatic, anomaly of the aortic arch, with right subclavian artery originating directly from the aorta, distal to the left subclavian artery, and taking a retroesophageal path route to its usual site to the right arm. The presence of ARSA poses numerous challenges for cerebral angiography and interventions conducted via the transradial approach (TRA) because it creates a very unfavourable path for catheterization of any epiaortic vessel.</p> Cases Description <p>Two cases of successful right transradial middle meningeal artery embolization (MMAe) in ARSA patients performed with an identical tricoaxial setup are described (first case unilateral and second case bilateral), with a thorough description of the technical procedures.</p> Conclusions <p>ARSA is a rare aortic arch anomaly often incidentally identified during aortic arch navigation at the beginning of MMAe procedure. If this information is known prior to performing transradial intervention, choosing an alternative vascular access is recommended, but since cross-sectional evaluation of epiaortic vessels before MMAe is not a routine clinical practice, a proper endovascular technique and material selection could feasibly overcome this rare and complex aortic arch anomaly </p>