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Purpose <p>Interstitial lung disease (ILD) is the most common pulmonary manifestation of systemic sclerosis (SSc) and is a cause of morbidity and mortality. Among imaging modalities, HRCT provides the highest spatial resolution and remains the preferred method for evaluating ILD in systemic sclerosis. To assess the extent and severity of ILD in SSc patients using HRCT scoring and correlate with pulmonary function test (PFT) parameters.</p> Methods <p>Clinically confirmed 45 patients with systemic sclerosis underwent HRCT evaluation. Disease severity was graded using Ooi’s semiquantitative scoring system and correlated with PFT findings. Data were analysed using SPSS v20.</p> Results <p>The mean age was 37.3 years, with having female predominance. NSIP was the most frequent pattern (64%), followed by UIP (24%). Mixed ground-glass and reticular opacities were the commonest HRCT findings (66.7%), with lower-lobe predominance. Most patients had mild to moderate restriction on PFT (FVC 61–80%). A significant inverse correlation was observed between HRCT score and FVC (<i>r</i> = − 0.61, <i>p</i> &lt; 0.05).</p> Conclusions <p>HRCT scoring is a reliable, non-invasive tool for assessing the severity and extent of ILD in systemic sclerosis. It correlates closely with pulmonary function and assists in disease monitoring and prognosis assessment.</p>

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Role of HRCT Scoring in the Evaluation of Interstitial Lung Diseases Associated with Systemic Sclerosis

  • 期刊论文

  • 发表日期：

    2026年4月10日

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  • Ruban Bansal,
  • Maheswar Chaudhury,
  • Beena Devi Agarwal,
  • Jayashree Mohanty,
  • Somadatta Das,
  • Ashis Kumar Satapathy

摘要

Purpose

Interstitial lung disease (ILD) is the most common pulmonary manifestation of systemic sclerosis (SSc) and is a cause of morbidity and mortality. Among imaging modalities, HRCT provides the highest spatial resolution and remains the preferred method for evaluating ILD in systemic sclerosis. To assess the extent and severity of ILD in SSc patients using HRCT scoring and correlate with pulmonary function test (PFT) parameters.

Methods

Clinically confirmed 45 patients with systemic sclerosis underwent HRCT evaluation. Disease severity was graded using Ooi’s semiquantitative scoring system and correlated with PFT findings. Data were analysed using SPSS v20.

Results

The mean age was 37.3 years, with having female predominance. NSIP was the most frequent pattern (64%), followed by UIP (24%). Mixed ground-glass and reticular opacities were the commonest HRCT findings (66.7%), with lower-lobe predominance. Most patients had mild to moderate restriction on PFT (FVC 61–80%). A significant inverse correlation was observed between HRCT score and FVC (r = − 0.61, p < 0.05).

Conclusions

HRCT scoring is a reliable, non-invasive tool for assessing the severity and extent of ILD in systemic sclerosis. It correlates closely with pulmonary function and assists in disease monitoring and prognosis assessment.