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Background <p>Nutritional risk has a significant influence on outcomes in critically ill patients, however, few scoring systems have been validated for use in intensive care populations.</p> Objective <p>To evaluate the association between the modified Nutrition Risk in Critically Ill (mNUTRIC) score and clinical outcomes in a mixed intensive care unit (ICU).</p> Methods <p>This post-hoc analysis utilized retrospective data from 602 adults who were admitted to the ICU at a tertiary hospital between January and September 2019. Patients were categorized into two groups based on their nutritional risk: high risk (mNUTRIC &gt; 4) and low risk (mNUTRIC ≤ 4). Data collected within 24&#xa0;h of ICU admission included various clinical, laboratory, and physiological parameters. Logistic regression was employed to evaluate the relationship between mNUTRIC scores and in-hospital mortality. The predictive accuracy of the model was assessed through receiver operating characteristic (ROC) analysis.</p> Results <p>Overall, in-hospital mortality was 43% (259/602). Nearly 70% of patients were at high nutritional risk. The mNUTRIC score independently predicted in-hospital mortality (odds ratio [OR], 1.60; 95% confidence interval [CI], 1.40–1.83; <i>p</i> &lt; 0.001). High nutritional risk patients had nearly fourfold higher mortality odds (OR 3.89; 95% CI 2.32–6.53; <i>p</i> &lt; 0.001). The score demonstrated moderate predictive accuracy (area under the ROC curve, 0.73; 95% CI 0.69–0.77), with an optimal cutoff of 6 (sensitivity 0.74; specificity 0.60).</p> Conclusion <p>A high nutritional risk, as identified by the mNUTRIC score, was independently associated with in-hospital mortality in a mixed ICU population. The score demonstrated moderate predictive value and may be useful for mortality risk stratification in critically ill patients.</p>

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Association between the Modified NUTRIC Score (mNUTRIC) and Clinical Outcomes in a Mixed Intensive Care Unit: A Retrospective Cohort Study

  • 期刊论文

  • 发表日期：

    2026年1月6日

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  • Thanh Luan Nguyen,
  • Quang Dai Le,
  • Trang Nguyen Hoai Dinh,
  • Van Hoang Nam Ho,
  • Cong Dang Tran,
  • Van Phieu Duong,
  • Hoang Ngoc Thao Duong,
  • Phuc Tuong Pham,
  • Thi Phuong Thao Le,
  • Tuyet Phuong Bui

摘要

Background

Nutritional risk has a significant influence on outcomes in critically ill patients, however, few scoring systems have been validated for use in intensive care populations.

Objective

To evaluate the association between the modified Nutrition Risk in Critically Ill (mNUTRIC) score and clinical outcomes in a mixed intensive care unit (ICU).

Methods

This post-hoc analysis utilized retrospective data from 602 adults who were admitted to the ICU at a tertiary hospital between January and September 2019. Patients were categorized into two groups based on their nutritional risk: high risk (mNUTRIC > 4) and low risk (mNUTRIC ≤ 4). Data collected within 24 h of ICU admission included various clinical, laboratory, and physiological parameters. Logistic regression was employed to evaluate the relationship between mNUTRIC scores and in-hospital mortality. The predictive accuracy of the model was assessed through receiver operating characteristic (ROC) analysis.

Results

Overall, in-hospital mortality was 43% (259/602). Nearly 70% of patients were at high nutritional risk. The mNUTRIC score independently predicted in-hospital mortality (odds ratio [OR], 1.60; 95% confidence interval [CI], 1.40–1.83; p < 0.001). High nutritional risk patients had nearly fourfold higher mortality odds (OR 3.89; 95% CI 2.32–6.53; p < 0.001). The score demonstrated moderate predictive accuracy (area under the ROC curve, 0.73; 95% CI 0.69–0.77), with an optimal cutoff of 6 (sensitivity 0.74; specificity 0.60).

Conclusion

A high nutritional risk, as identified by the mNUTRIC score, was independently associated with in-hospital mortality in a mixed ICU population. The score demonstrated moderate predictive value and may be useful for mortality risk stratification in critically ill patients.