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Background <p>Patent ductus arteriosus (PDA) is a cardiovascular injury that occurs during perinatal asphyxia.</p> Objectives <p>This study aimed to document the prevalence of PDA in perinatal asphyxia patients and to identify associated factors.</p> Methods <p>This observational study was conducted in a tertiary health setting among newborns with perinatal asphyxia. Echocardiography was used to detect the PDA among the newborns.</p> Results <p>The prevalence of PDA in newborns with perinatal asphyxia was 17.9%. A significant association was observed between age in days and the presence of PDA. <i>X</i><sup>2</sup> = 10.04, <i>p</i> = 0.007. No significant association was found between sex and new-borns with perinatal asphyxia who had PDA. No significant association was found between gestational age and the presence of PDA.<i> X</i><sup>2</sup> = 2.32 <i>p</i> = 0.127. However, among newborns with perinatal asphyxia who delivered at an earlier gestational age (37–40&#xa0;weeks), 12 (80.0%) had more PDA than did those who delivered at a later GA (40–42&#xa0;weeks), 12 (80.0%).</p> Conclusion <p>The prevalence of PDA in asphyxiated newborns is high. Early recognition of the existence of a PDA during birth asphyxia and appropriate intervention could help alleviate the adverse effects following the disease. This intervention includes addressing the complications of PDA in perinatal asphyxia, tailoring medical care, and improving clinical outcomes.</p> <p>The study revealed that approximately one-third of new-borns with birth asphyxia had moderate PAH, and most of them also had either right-to-left shunts or bidirectional shunting.</p>

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Patent Ductus arteriosus and Factors Associated with its Occurrence in Newborns with Perinatal Asphyxia Attending a Teaching Hospital in Southeast Nigeria

  • 期刊论文

  • 发表日期：

    2025年10月1日

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  • Josephat M. Chinawa,
  • Okechukwu S. Ani,
  • Awoere T. Chinawa,
  • Francis N. Ogbuka,
  • Philip C. Elobuike,
  • Odetunde I. Odutola

摘要

Background

Patent ductus arteriosus (PDA) is a cardiovascular injury that occurs during perinatal asphyxia.

Objectives

This study aimed to document the prevalence of PDA in perinatal asphyxia patients and to identify associated factors.

Methods

This observational study was conducted in a tertiary health setting among newborns with perinatal asphyxia. Echocardiography was used to detect the PDA among the newborns.

Results

The prevalence of PDA in newborns with perinatal asphyxia was 17.9%. A significant association was observed between age in days and the presence of PDA. X2 = 10.04, p = 0.007. No significant association was found between sex and new-borns with perinatal asphyxia who had PDA. No significant association was found between gestational age and the presence of PDA. X2 = 2.32 p = 0.127. However, among newborns with perinatal asphyxia who delivered at an earlier gestational age (37–40 weeks), 12 (80.0%) had more PDA than did those who delivered at a later GA (40–42 weeks), 12 (80.0%).

Conclusion

The prevalence of PDA in asphyxiated newborns is high. Early recognition of the existence of a PDA during birth asphyxia and appropriate intervention could help alleviate the adverse effects following the disease. This intervention includes addressing the complications of PDA in perinatal asphyxia, tailoring medical care, and improving clinical outcomes.

The study revealed that approximately one-third of new-borns with birth asphyxia had moderate PAH, and most of them also had either right-to-left shunts or bidirectional shunting.