Scholarlink

<b>Introduction</b> <p>Neuroblastoma is the most common extracranial solid tumor of childhood and typically originates in the adrenal medulla or along the sympathetic chain. Pelvic neuroblastomas are exceptionally rare, and presentation with acute urinary retention is rarer still. Prompt recognition of such atypical presentations is critical for preventing neurologic and urologic complications.</p> <b>Case Presentation</b> <p>A 9-month-old girl presented with acute urinary retention. Imaging (CT and MRI) revealed a large, heterogeneously enhancing presacral mass extending through the neural foramina into the spinal canal, with associated sacral bone erosion. Urinary vanillylmandelic acid and homovanillic acid levels were markedly elevated. Core-needle biopsy confirmed poorly differentiated neuroblastoma with unfavorable histology. Multidisciplinary management—including surgical debulking followed by adjuvant chemotherapy—was initiated, leading to gradual improvement in bladder function.</p> <b>Conclusions</b> <p>Pelvic (presacral) neuroblastoma should be considered in infants who present with unexplained urinary retention. Early imaging, catecholamine metabolite testing, and coordinated surgical–oncologic care are essential to optimize both functional and oncologic outcomes.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Presacral Neuroblastoma Presenting as Acute Urinary Retention in an Infant: A Case Report

  • 期刊论文

  • 发表日期：

    2025年7月21日

查看全文
  • Omar Sawafta,
  • Ammar Hassouneh,
  • Jehad Khamaysa,
  • Yazan Sawafta,
  • Husam Hamshary,
  • Yaqoot Anabseh,
  • Yazan Dibas,
  • Mohammad Bdair

摘要

Introduction

Neuroblastoma is the most common extracranial solid tumor of childhood and typically originates in the adrenal medulla or along the sympathetic chain. Pelvic neuroblastomas are exceptionally rare, and presentation with acute urinary retention is rarer still. Prompt recognition of such atypical presentations is critical for preventing neurologic and urologic complications.

Case Presentation

A 9-month-old girl presented with acute urinary retention. Imaging (CT and MRI) revealed a large, heterogeneously enhancing presacral mass extending through the neural foramina into the spinal canal, with associated sacral bone erosion. Urinary vanillylmandelic acid and homovanillic acid levels were markedly elevated. Core-needle biopsy confirmed poorly differentiated neuroblastoma with unfavorable histology. Multidisciplinary management—including surgical debulking followed by adjuvant chemotherapy—was initiated, leading to gradual improvement in bladder function.

Conclusions

Pelvic (presacral) neuroblastoma should be considered in infants who present with unexplained urinary retention. Early imaging, catecholamine metabolite testing, and coordinated surgical–oncologic care are essential to optimize both functional and oncologic outcomes.