Objective <p>of this study is to describe the clinical application and outcomes of scleral patch grafts in managing corneal perforations, particularly in settings with limited access to donor corneal tissue.</p> Methods <p>A case series of three patients with corneal perforation managed using scleral patch grafts was presented, accompanied by a literature review. The indication for scleral grafting included infective keratitis in two cases and sterile corneal melt in one case. All cases were treated in a resource-limited setting where donor corneas were unavailable at the time of presentation.</p> Results <p>All three cases achieved successful anatomical restoration following scleral patch grafting. Case 3 required a secondary procedure due to graft failure. Cases 1 and 2 subsequently underwent optical penetrating keratoplasty, which resulted in favourable visual outcomes. The scleral patch graft served as a temporary but effective measure to preserve globe integrity and prevent further complications until definitive treatment could be performed in resource-constrained settings.</p> Conclusions <p>Scleral patch grafting is a viable temporizing option for the management of corneal perforations when donor corneal tissue is unavailable. It provides structural support, preserves ocular integrity, and facilitates subsequent optical keratoplasty, making it a valuable intervention in resource-constrained settings.</p>