Scholarlink

<p>Multiple myeloma (MM) represents 10% of hematologic malignancies and 1% of all cancers. In MM, spinal involvement can occur in up to 50–60% of patients, presenting a diverse range of challenges, from symptomatic lytic lesions, fractures, spinal cord compression syndrome (SCCS), to even asymptomatic imaging findings. We present this guide for diagnosing and treating spinal injuries due to MM and plasmacytoma performed by spine surgeons at different hospital centers. Based on the current literature and a systematic literature review with PRISMA guidelines, we performed this treatment algorithm for spine fractures due to multiple myeloma and plasmacytoma. We obtained 75 papers for final review and created a new classification for MM spine fractures. This guide intends to create a new classification for vertebral fractures due to MM, which is significant as it provides a more comprehensive and standardized approach to diagnosing and treating these fractures. It also includes recommendations for diagnosis, management, and treatment in these patients. This guideline provides actionable recommendations tailored to different fracture types and levels of severity, all supported by a robust, evidence-based logic. This makes the guidelines not only applicable but also reliable for clinicians across various levels of expertise and settings.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

International Consensus for the Management of Spinal Lesions Due to Multiple Myeloma and Plasmacytoma: Belt and Road Algorithm and Systematic Literature Review

  • 期刊论文

  • 发表日期：

    2025年5月29日

查看全文
  • Daniel Alejandro Vega-Moreno,
  • Julio César López-Valdés,
  • Chau Hong Him Dickson,
  • Muhamad Aulia Rahman,
  • Ali Akar,
  • Sylvio Mistro Neto,
  • Renato Estuardo Guerra Escobar,
  • Eguchi Kaoru,
  • William Limoa,
  • Muhammad Fahriza,
  • Nicephorus Rutabasibwa,
  • Yu XiaoJun,
  • Mayank Nakipuria,
  • Dragan Jankovic,
  • Manuel de Jesús Encarnación-Ramírez,
  • Alejandro Rodriguez-Camacho,
  • Mónica Serrano Murillo,
  • Mistral Castellanos-Mares,
  • Aldo José Salazar-Barsia,
  • Gervith Reyes-Soto

摘要

Multiple myeloma (MM) represents 10% of hematologic malignancies and 1% of all cancers. In MM, spinal involvement can occur in up to 50–60% of patients, presenting a diverse range of challenges, from symptomatic lytic lesions, fractures, spinal cord compression syndrome (SCCS), to even asymptomatic imaging findings. We present this guide for diagnosing and treating spinal injuries due to MM and plasmacytoma performed by spine surgeons at different hospital centers. Based on the current literature and a systematic literature review with PRISMA guidelines, we performed this treatment algorithm for spine fractures due to multiple myeloma and plasmacytoma. We obtained 75 papers for final review and created a new classification for MM spine fractures. This guide intends to create a new classification for vertebral fractures due to MM, which is significant as it provides a more comprehensive and standardized approach to diagnosing and treating these fractures. It also includes recommendations for diagnosis, management, and treatment in these patients. This guideline provides actionable recommendations tailored to different fracture types and levels of severity, all supported by a robust, evidence-based logic. This makes the guidelines not only applicable but also reliable for clinicians across various levels of expertise and settings.