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<p>In our previous report, we identified advanced hepatocellular carcinoma as a prognostic factor for gastroesophageal varices following endoscopic treatment. In this study, we aimed to identify prognostic factors for gastroesophageal varices after endoscopic treatment in patients without advanced hepatocellular carcinoma. Kaplan–Meier and Cox proportional hazards models were used to determine the prognostic factors in 263 patients with chronic liver diseases without advanced hepatocellular carcinoma who underwent endoscopic therapy for gastroesophageal varices. After endoscopic treatment, the cumulative overall survival rates for gastroesophageal varices in patients without advanced hepatocellular carcinoma were 90.28%, 79.17%, and 69.56% at 1, 3, and 5&#xa0;years, respectively. The prognostic factors associated with this treatment were age, etiology, and albumin-bilirubin grade. The presence of non-advanced hepatocellular carcinoma was not associated with prognosis. Managing hepatocellular carcinoma and maintaining sufficient liver function are crucial for long-term survival following endoscopic treatment for gastroesophageal varices.</p>

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Prognostic Factors for Gastroesophageal Varices After Endoscopic Treatment in Patients Without Advanced Hepatocellular Carcinoma

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年5月7日

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  • Ikuya Sugiura,
  • Toshiyuki Baba,
  • Shojiro Uozumi,
  • Hitoshi Yoshida

摘要

In our previous report, we identified advanced hepatocellular carcinoma as a prognostic factor for gastroesophageal varices following endoscopic treatment. In this study, we aimed to identify prognostic factors for gastroesophageal varices after endoscopic treatment in patients without advanced hepatocellular carcinoma. Kaplan–Meier and Cox proportional hazards models were used to determine the prognostic factors in 263 patients with chronic liver diseases without advanced hepatocellular carcinoma who underwent endoscopic therapy for gastroesophageal varices. After endoscopic treatment, the cumulative overall survival rates for gastroesophageal varices in patients without advanced hepatocellular carcinoma were 90.28%, 79.17%, and 69.56% at 1, 3, and 5 years, respectively. The prognostic factors associated with this treatment were age, etiology, and albumin-bilirubin grade. The presence of non-advanced hepatocellular carcinoma was not associated with prognosis. Managing hepatocellular carcinoma and maintaining sufficient liver function are crucial for long-term survival following endoscopic treatment for gastroesophageal varices.