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<p>The increasing demand for biosensors has prompted an investigation into organic transistors as viable options for these applications, owing to their flexibility, biodegradability, cost-effectiveness, low-temperature fabrication processes, and compatibility with various substrates. This article presents a dual-cavity dielectric modulated organic thin-film transistor (DCDMOTFT) that can detect a range of biomolecules, making it a suitable candidate for biosensing applications. The device has been calibrated using fabricated work, and these calibrated parameters are used for simulation. In the proposed structure, the dual cavity has been created in the oxide under the gate electrode to sense the biomolecules. The presence of biomolecules in the cavity can lead to changes in capacitance and interface charge density, which influence device electrostatics, including channel potential, band bending, and electrical parameters. The device’s sensitivity is calculated by evaluating the variation in ON current with various biomolecules compared to the reference (K = 1). Additionally, the impact of variations in gate work function (WF) indicates that sensitivity diminishes as WF increases. It has been shown that the Drain current sensitivity is 880% increased for neutral (ρ) and 168.16% increased for negatively charged (ρ = -1 × 10<sup>12</sup>&#xa0;cm-2) biomolecules for V<sub>DS</sub> = -1.5&#xa0;V and V<sub>GS</sub> = -3.0&#xa0;V at K = 12. The proposed biosensor demonstrates enhanced biomolecule detection capabilities compared to existing DM-OTFT&#xa0;biosensors, showcasing high sensitivity, affordability, and biocompatibility.</p>

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To Design Dual Cavity Dielectric Modulated Organic Thin-Film Transistor (DCDMOTFT) for Label-Free Biosensing Applications

  • 期刊论文

  • 发表日期：

    2026年1月27日

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  • Somvir Jakher,
  • Rekha Yadav

摘要

The increasing demand for biosensors has prompted an investigation into organic transistors as viable options for these applications, owing to their flexibility, biodegradability, cost-effectiveness, low-temperature fabrication processes, and compatibility with various substrates. This article presents a dual-cavity dielectric modulated organic thin-film transistor (DCDMOTFT) that can detect a range of biomolecules, making it a suitable candidate for biosensing applications. The device has been calibrated using fabricated work, and these calibrated parameters are used for simulation. In the proposed structure, the dual cavity has been created in the oxide under the gate electrode to sense the biomolecules. The presence of biomolecules in the cavity can lead to changes in capacitance and interface charge density, which influence device electrostatics, including channel potential, band bending, and electrical parameters. The device’s sensitivity is calculated by evaluating the variation in ON current with various biomolecules compared to the reference (K = 1). Additionally, the impact of variations in gate work function (WF) indicates that sensitivity diminishes as WF increases. It has been shown that the Drain current sensitivity is 880% increased for neutral (ρ) and 168.16% increased for negatively charged (ρ = -1 × 1012 cm-2) biomolecules for VDS = -1.5 V and VGS = -3.0 V at K = 12. The proposed biosensor demonstrates enhanced biomolecule detection capabilities compared to existing DM-OTFT biosensors, showcasing high sensitivity, affordability, and biocompatibility.