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<p>This study demonstrates a novel approach for fabricating multifunctional contact lenses by integrating gold (Au) and platinum (Pt) nanozymes (NZs) possessing oxidoreductase-like activities into 3D-printed contact lenses to serve oxidative stress modulation and color blindness management applications. The material properties of the lenses were thoroughly characterized through FTIR, XPS, SEM, EDS, and wettability analyses, which confirmed successful incorporation of NZs and results consistent with the literature and/or control samples. The catalytic activity of both Au and Pt NZs was verified by assessing the degradation of methylene blue (MB) in the presence of hydrogen peroxide. The localized surface plasmon resonance (LSPR) of Au NZs was red-shifted by increasing the concentration of Au NZs, to achieve filtering within the red-green color blindness range. In addition, the work examines the interplay between their multi-material characteristics and their thermal, rheological, and mechanical properties. Overall, multifunctional multi-material contact lenses have potential applications in biomedical fields, particularly in oxidative stress reduction and color vision management.</p>

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Platinum nanozymes loaded contact lenses: screening of oxidoreductase activities and efficient degradation of organic dye

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年7月30日

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  • Said El Turk,
  • Mohammed Ayaz Uddin,
  • Aswathi Ram P.,
  • Afra Almeraikhi,
  • Aisha T. Khaleel,
  • Valentyn S. Volkov,
  • Andreas Schiffer,
  • Wael Zaki,
  • Haider Butt

摘要

This study demonstrates a novel approach for fabricating multifunctional contact lenses by integrating gold (Au) and platinum (Pt) nanozymes (NZs) possessing oxidoreductase-like activities into 3D-printed contact lenses to serve oxidative stress modulation and color blindness management applications. The material properties of the lenses were thoroughly characterized through FTIR, XPS, SEM, EDS, and wettability analyses, which confirmed successful incorporation of NZs and results consistent with the literature and/or control samples. The catalytic activity of both Au and Pt NZs was verified by assessing the degradation of methylene blue (MB) in the presence of hydrogen peroxide. The localized surface plasmon resonance (LSPR) of Au NZs was red-shifted by increasing the concentration of Au NZs, to achieve filtering within the red-green color blindness range. In addition, the work examines the interplay between their multi-material characteristics and their thermal, rheological, and mechanical properties. Overall, multifunctional multi-material contact lenses have potential applications in biomedical fields, particularly in oxidative stress reduction and color vision management.