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Purposes <p>Older patients are often perceived as being at higher risk of poor post-ICU outcomes, yet data describing their multidimensional clinical profile within structured follow-up programs remain limited.</p> Methods <p>We conducted a retrospective analysis of prospectively collected data from a single-center, post-ICU follow-up clinic. All ICU survivors attending a standardized 3-month (M3) consultation between 2022 and 2025 were eligible. Patients were divided into geriatric (≥ 65&#xa0;years) and non-geriatric (&lt; 65&#xa0;years) groups. Outcomes included cognitive function (MoCA), psychological symptoms (HADS, IES-R), sleep quality (PSQI), functional status (Barthel Index), physical activity (IPAQ-SF), frailty (Clinical Frailty Scale), and health-related quality of life (EQ-5D-3L). Multivariate linear regression was used to explore associations between age and post-ICU outcomes.</p> Results <p>A total of 257 patients were analyzed, including 107 older and 150 younger survivors. Functional independence, physical activity, frailty, and return to daily activities were comparable between groups. Geriatric survivors reported fewer anxiety, depressive, and post-traumatic stress symptoms, despite slightly lower cognitive performance. Quality of life was preserved and modestly higher in geriatric patients. In multivariate analysis, age was independently associated only with cognitive performance (lower MoCA scores) and post-traumatic stress symptoms (lower IES-R scores), and not with other PICS domains.</p> Conclusion <p>At M3 after ICU discharge, older and younger survivors engaged in structured follow-up care showed broadly similar clinical and functional profiles although older age was selectively associated with lower cognitive performance and fewer post-traumatic stress symptoms. While these findings do not reflect recovery trajectories, they support comprehensive, individualized assessment beyond chronological age in post-ICU care.</p>

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A cross-sectional analysis of multidimensional clinical profiles of older adults engaged in structured post-ICU follow-up: age is not the whole story

  • 期刊论文

  • 发表日期：

    2026年6月2日

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  • Anne-Françoise Rousseau,
  • Bertrand Guidet,
  • Camille Colson,
  • Pauline Minguet,
  • Sarah Neis-Gilson,
  • Aurélie Wagener,
  • Bernard Lambermont

摘要

Purposes

Older patients are often perceived as being at higher risk of poor post-ICU outcomes, yet data describing their multidimensional clinical profile within structured follow-up programs remain limited.

Methods

We conducted a retrospective analysis of prospectively collected data from a single-center, post-ICU follow-up clinic. All ICU survivors attending a standardized 3-month (M3) consultation between 2022 and 2025 were eligible. Patients were divided into geriatric (≥ 65 years) and non-geriatric (< 65 years) groups. Outcomes included cognitive function (MoCA), psychological symptoms (HADS, IES-R), sleep quality (PSQI), functional status (Barthel Index), physical activity (IPAQ-SF), frailty (Clinical Frailty Scale), and health-related quality of life (EQ-5D-3L). Multivariate linear regression was used to explore associations between age and post-ICU outcomes.

Results

A total of 257 patients were analyzed, including 107 older and 150 younger survivors. Functional independence, physical activity, frailty, and return to daily activities were comparable between groups. Geriatric survivors reported fewer anxiety, depressive, and post-traumatic stress symptoms, despite slightly lower cognitive performance. Quality of life was preserved and modestly higher in geriatric patients. In multivariate analysis, age was independently associated only with cognitive performance (lower MoCA scores) and post-traumatic stress symptoms (lower IES-R scores), and not with other PICS domains.

Conclusion

At M3 after ICU discharge, older and younger survivors engaged in structured follow-up care showed broadly similar clinical and functional profiles although older age was selectively associated with lower cognitive performance and fewer post-traumatic stress symptoms. While these findings do not reflect recovery trajectories, they support comprehensive, individualized assessment beyond chronological age in post-ICU care.