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<p>Personalized nutritional adaption and an individualized exercise program represent promising tools for the therapy of sarcopenia in patients with advanced liver disease. Sarcopenia is associated with the progression of liver disease including increased mortality and risk of complications. Accordingly, every patient with liver disease should be screened for the presence of sarcopenia or malnutrition and, if necessary, be referred to a&#xa0;dietician. In combination with supervised and individually tuned exercise, these measures can significantly improve cardiorespiratory fitness, muscle strength, mobility, and quality of life. For the treatment of metabolic dysfunction-associated steatotic liver disease (MASLD) and metabolic dysfunction-associated steatohepatitis (MASH), a&#xa0;weight reduction of up to 10% is recommended. In this context, a&#xa0;Mediterranean diet rich of fiber, the reduction of sugar, fructose, and refined carbohydrates as well as the avoidance of ultraprocessed foods are recommended. Through a&#xa0;combination of a&#xa0;well-balanced diet with a&#xa0;wide variety of natural food and exercise training, liver function can be sustainably improved. A&#xa0;patient-centered exercise program, tailored to the individual’s capacity and capabilities, helps to maintain a&#xa0;healthy lifestyle and has positive effects on liver health independent of weight loss. A&#xa0;multidisciplinary approach involving exercise specialists, dieticians, and psychologists is conducive to successfully managing the social, economic, and psychological challenges of lifestyle change.</p>

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Ernährung und körperliches Training bei Lebererkrankungen

  • 期刊论文

  • 发表日期：

    2025年4月16日

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  • Thomas-Matthias Scherzer,
  • Bettina Knabl,
  • Benedikt Mehl

摘要

Personalized nutritional adaption and an individualized exercise program represent promising tools for the therapy of sarcopenia in patients with advanced liver disease. Sarcopenia is associated with the progression of liver disease including increased mortality and risk of complications. Accordingly, every patient with liver disease should be screened for the presence of sarcopenia or malnutrition and, if necessary, be referred to a dietician. In combination with supervised and individually tuned exercise, these measures can significantly improve cardiorespiratory fitness, muscle strength, mobility, and quality of life. For the treatment of metabolic dysfunction-associated steatotic liver disease (MASLD) and metabolic dysfunction-associated steatohepatitis (MASH), a weight reduction of up to 10% is recommended. In this context, a Mediterranean diet rich of fiber, the reduction of sugar, fructose, and refined carbohydrates as well as the avoidance of ultraprocessed foods are recommended. Through a combination of a well-balanced diet with a wide variety of natural food and exercise training, liver function can be sustainably improved. A patient-centered exercise program, tailored to the individual’s capacity and capabilities, helps to maintain a healthy lifestyle and has positive effects on liver health independent of weight loss. A multidisciplinary approach involving exercise specialists, dieticians, and psychologists is conducive to successfully managing the social, economic, and psychological challenges of lifestyle change.