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<p>Riedel’s thyroiditis is a&#xa0;very rare thyroid disease and is likely still underdiagnosed. It is classified as an IgG4-associated disease, although it very rarely occurs as part of an IgG4-associated systemic disease (&lt; 4%) and, unlike these diseases, shows a&#xa0;female predominance.</p><p>Diagnosis is difficult and always requires histological confirmation, including immunohistochemical confirmation as well as the exclusion of malignancy.</p><p>Therapeutically, the disease generally responds well to glucocorticoids. Immunosuppressants (primarily B‑cell-depleting therapies) are used as a&#xa0;glucocorticoid-sparing alternative or as an adjunct, as well as in cases of relapsing or glucocorticoid-refractory disease.</p>

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Die Riedel-Thyreoiditis –selten, vergessen oder nur übersehen?

  • 期刊论文

  • 发表日期：

    2026年7月31日

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  • Kerstin Murgg,
  • Alice Pap,
  • Raimund Lunzer,
  • Rudolf Stacher,
  • Karl Fritz,
  • Eva Petnehazy,
  • Wolfgang Buchinger,
  • Jan Bucerius

摘要

Riedel’s thyroiditis is a very rare thyroid disease and is likely still underdiagnosed. It is classified as an IgG4-associated disease, although it very rarely occurs as part of an IgG4-associated systemic disease (< 4%) and, unlike these diseases, shows a female predominance.

Diagnosis is difficult and always requires histological confirmation, including immunohistochemical confirmation as well as the exclusion of malignancy.

Therapeutically, the disease generally responds well to glucocorticoids. Immunosuppressants (primarily B‑cell-depleting therapies) are used as a glucocorticoid-sparing alternative or as an adjunct, as well as in cases of relapsing or glucocorticoid-refractory disease.