<p>The intergenerational transmission of anxiety and depression is well-documented, but the specific pathways remain less understood. This study examined the role of intolerance of uncertainty (IU) as a transdiagnostic mechanism in this transmission. We recruited 966 children aged 9–13 and their mothers from two primary schools in China using convenience sampling. Maternal and child IU, anxiety, and depression were assessed, and structural equation modeling was employed to analyze the data. Results indicated that the direct path linking maternal and child IU, rather than maternal or child IU alone, mediated the relationship between maternal and child anxiety and depression. These findings suggest that the intergenerational link between cognitive vulnerabilities, such as IU, is critical in perpetuating anxiety and depression across generations. Future research is needed to confirm these findings and further elucidate the mechanisms involved to develop effective prevention and intervention strategies aimed at breaking the cycle of psychopathology across generations.</p>

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The Transdiagnostic Process Contributing to the Intergenerational Transmission of Depressive and Anxiety Symptoms: Maternal and Child Intolerance of Uncertainty

  • Nisha Yao,
  • Tomoko Kishimoto

摘要

The intergenerational transmission of anxiety and depression is well-documented, but the specific pathways remain less understood. This study examined the role of intolerance of uncertainty (IU) as a transdiagnostic mechanism in this transmission. We recruited 966 children aged 9–13 and their mothers from two primary schools in China using convenience sampling. Maternal and child IU, anxiety, and depression were assessed, and structural equation modeling was employed to analyze the data. Results indicated that the direct path linking maternal and child IU, rather than maternal or child IU alone, mediated the relationship between maternal and child anxiety and depression. These findings suggest that the intergenerational link between cognitive vulnerabilities, such as IU, is critical in perpetuating anxiety and depression across generations. Future research is needed to confirm these findings and further elucidate the mechanisms involved to develop effective prevention and intervention strategies aimed at breaking the cycle of psychopathology across generations.