We are studying the stationary quantum Zakharov systems 1 \(\begin{aligned} \left\{ \begin{array}{ll} \Delta ^2u-\Delta u+W_\lambda (x) u+\beta \phi u=g(x,u), & \quad x\in {\mathbb {R}}^3,\\ -\Delta \phi +\phi =u^2,& \quad x\in {\mathbb {R}}^3,\\ \end{array} \right. \end{aligned}\) where \(\Delta ^2:=\Delta (\Delta )\) and \(W_\lambda (x)=\lambda W^+(x)-W^-(x)\) with \(W^{\pm }(x)=\max \lbrace \pm W(x),0\rbrace \) . Under suitable assumptions, we prove the existence of nontrivial solution for \(\lambda \) large enough. Our main contribution is to consider stationary quantum Zakharov system taking into account the case where \(\beta \in {\mathbb {R}}\) , particularly, if \(\beta <0,\) we are keen to determine whether Problem (1) has at least one solution considering the interaction between the terms g(x, u) and \(\beta \phi u.\) Our results extend the related results in the literature (e.g., Example Sun et al. in Appl Math Lett 95:172–178, 2019; Benhana in Complex Variables Elliptic Equ. https://doi.org/10.1080/17476933.2023.2229736. 2023).