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<p>This study aimed to quantitatively evaluate the volume of internal voids and gaps at the dentin-material interface in different MTA-based biomaterials used for apexification treatment using micro-CT imaging. Forty human maxillary incisors were used in the study. Immature tooth simulation was achieved for apexification modeling. Next, the teeth were randomly divided into four groups (<i>n</i> = 10), and a different apexification material was used for each group. In Group 1, MTA Flow (Ultradent, Utah, USA); in Group 2, Ortho MTA (BioMTA, Seoul, Korea); in Group 3, EndoCEM MTA (Maruchi, Gangwon-Do, Korea); in Group 4, MTA Angelus (Angelus, Londrina, Brazil) were placed orthograde in the 3&#xa0;mm region apically following the manufacturer’s instructions. After 2 weeks, the samples were scanned using a micro-CT device to examine interface gaps and internal voids. After the reconstruction, the total material volume in the apexification area, the amount of space in the material, and the amount of space between the material and dentin were quantified as mm³. The Shapiro-Wilk test, ANOVA, and Levene’s test were used to evaluate the statistical measurements. Statistical significance was set at <i>p</i> &lt; 0.05. Although Ortho MTA showed numerically higher interface gap values, no statistically significant differences were detected among Ortho MTA, MTA Flow, and MTA Angelus (one-way ANOVA, <i>p</i> = 0.178). A significant pairwise difference was observed only between Ortho MTA and EndoCem MTA(post hoc Tukey test, <i>p</i> &lt; 0.05). No significant differences were found among the groups regarding internal void volumes (<i>p</i> = 0.755).</p>

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Evaluation of interface gaps and internal voids in MTA-based biomaterials used for apexification with micro-CT

  • 期刊论文

  • 发表日期：

    2025年9月12日

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  • Huda Melike Bayram

摘要

This study aimed to quantitatively evaluate the volume of internal voids and gaps at the dentin-material interface in different MTA-based biomaterials used for apexification treatment using micro-CT imaging. Forty human maxillary incisors were used in the study. Immature tooth simulation was achieved for apexification modeling. Next, the teeth were randomly divided into four groups (n = 10), and a different apexification material was used for each group. In Group 1, MTA Flow (Ultradent, Utah, USA); in Group 2, Ortho MTA (BioMTA, Seoul, Korea); in Group 3, EndoCEM MTA (Maruchi, Gangwon-Do, Korea); in Group 4, MTA Angelus (Angelus, Londrina, Brazil) were placed orthograde in the 3 mm region apically following the manufacturer’s instructions. After 2 weeks, the samples were scanned using a micro-CT device to examine interface gaps and internal voids. After the reconstruction, the total material volume in the apexification area, the amount of space in the material, and the amount of space between the material and dentin were quantified as mm³. The Shapiro-Wilk test, ANOVA, and Levene’s test were used to evaluate the statistical measurements. Statistical significance was set at p < 0.05. Although Ortho MTA showed numerically higher interface gap values, no statistically significant differences were detected among Ortho MTA, MTA Flow, and MTA Angelus (one-way ANOVA, p = 0.178). A significant pairwise difference was observed only between Ortho MTA and EndoCem MTA(post hoc Tukey test, p < 0.05). No significant differences were found among the groups regarding internal void volumes (p = 0.755).