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<p>Acute myocardial infarction (AMI) is the most severe type of cardiovascular and cerebrovascular diseases (CVDs). Therefore, it is critical to identify markers related to the occurrence, development, and prognosis of AMI. Electrochemiluminescence (ECL) involves forming excited state species through electron transfer, which results in the emission of light. ECL sensors do not require an additional light source and have been widely explored for the detection of AMI markers due to their high sensitivity and specificity. Here, based on the three types of recognition elements (immunity, aptamer, and specific nucleic acid) found in ECL sensors, we review their recent detection of AMI markers and analyze the challenges and prospects of their future application in this field.</p>

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Recognition-Mediated Electrochemiluminescence Sensors: Recent Five-Year Breakthroughs and Future Directions in Acute Myocardial Infarction Biomarker Analysis

  • 期刊论文

  • 发表日期：

    2026年7月11日

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  • Shan Nan,
  • Ziyu Zhu,
  • Yao Xie,
  • Fan Wang,
  • Tianjian Lv,
  • Yuan Gao,
  • Pengyu Wang,
  • Heao Zhang,
  • Axin Liang

摘要

Acute myocardial infarction (AMI) is the most severe type of cardiovascular and cerebrovascular diseases (CVDs). Therefore, it is critical to identify markers related to the occurrence, development, and prognosis of AMI. Electrochemiluminescence (ECL) involves forming excited state species through electron transfer, which results in the emission of light. ECL sensors do not require an additional light source and have been widely explored for the detection of AMI markers due to their high sensitivity and specificity. Here, based on the three types of recognition elements (immunity, aptamer, and specific nucleic acid) found in ECL sensors, we review their recent detection of AMI markers and analyze the challenges and prospects of their future application in this field.