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<p>Metal-organic frameworks (MOFs), featuring tunable composition, high porosity, and easy, specific design and regulation, offer great potential for the fabrication of high-performance MOF-based optical sensor devices for diverse applications, including food safety. This review aims to provide a comprehensive, up-to-date summary of the engineered design and precise regulation of MOFs, including grafting functional monomers, doping metal nodes, and encapsulated guest units. The focus is on their applications in optical sensing and incorporating novel portable optical devices. Firstly, the precision-designed MOFs to construct luminescent sensors (fluorescence sensors and electrochemiluminescence (ECL) sensors), colorimetric sensors, and SERS sensors are described in detail. Then, some key applications of MOF-based materials were evaluated based on their different properties. Moreover, portable devices based on MOFs are also discussed in depth, including microfluidic systems, hydrogel sensing platforms, and test strip technologies. Finally, the challenges and opportunities for further development and practical applications of MOF-based optical sensors are summarized.</p>

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Precision-Designed Metal-Organic Frameworks (MOFs) in Constructing Optical Sensor Devices and their Applications

  • 期刊论文

  • 发表日期：

    2026年2月2日

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  • Mingping Shen,
  • Lu Zhang,
  • Fanxing Meng,
  • Zongda Li,
  • Jingkang Wang,
  • Ao Li,
  • Liang Wang,
  • Yanan Qin,
  • Chengyi Hou,
  • Minwei Zhang

摘要

Metal-organic frameworks (MOFs), featuring tunable composition, high porosity, and easy, specific design and regulation, offer great potential for the fabrication of high-performance MOF-based optical sensor devices for diverse applications, including food safety. This review aims to provide a comprehensive, up-to-date summary of the engineered design and precise regulation of MOFs, including grafting functional monomers, doping metal nodes, and encapsulated guest units. The focus is on their applications in optical sensing and incorporating novel portable optical devices. Firstly, the precision-designed MOFs to construct luminescent sensors (fluorescence sensors and electrochemiluminescence (ECL) sensors), colorimetric sensors, and SERS sensors are described in detail. Then, some key applications of MOF-based materials were evaluated based on their different properties. Moreover, portable devices based on MOFs are also discussed in depth, including microfluidic systems, hydrogel sensing platforms, and test strip technologies. Finally, the challenges and opportunities for further development and practical applications of MOF-based optical sensors are summarized.