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Purpose <p>This study evaluated the effect of low-level laser therapy (LLLT) on pain resulting from interproximal stripping in orthodontic patients.</p> Methods <p>In this double-blind, parallel-group randomized controlled trial, 21 orthodontic patients requiring interproximal stripping were randomly assigned to three groups (<i>n</i> = 7 each): LLLT (940&#xa0;nm laser, 32&#xa0;J/cm², 180&#xa0;s, applied to labial and lingual surfaces of the anterior mandible), placebo (laser in off mode), and control (no laser). Pain levels were assessed using a visual analog scale (VAS) at 3, 24, and 72&#xa0;h post-treatment. Data were analyzed using SPSS with an alpha level of 0.05.</p> Results <p>At 3&#xa0;h post-treatment, patients in the LLLT group reported no pain (VAS = 0 at all time points). The placebo group experienced mild pain (VAS = 0.43 ± 0.53), while the control group reported significantly higher pain levels (VAS = 2.29 ± 0.76). Pain scores in the control group continued to decrease over time (VAS = 1.14 ± 0.90 at 3&#xa0;h, 0.57 ± 0.79 at 24&#xa0;h, and 0.14 ± 0.38 at 72&#xa0;h). A significant difference in pain scores was observed among the three groups after adjusting for demographics and oral hygiene (<i>P</i> &lt; 0.001). The LLLT and placebo groups had significantly lower mean pain scores compared to the control group (<i>P</i> &lt; 0.001), but there was no significant difference between the LLLT and placebo groups (<i>P</i> = 1.00).</p> Conclusion <p>LLLT effectively reduced pain associated with interproximal stripping in orthodontic patients. However, the placebo treatment yielded similar pain relief, suggesting a potential placebo effect.</p> Clinical Trial Registration <p>Iranian Registry of Clinical Trials (IRCT20130812014333N192).</p>

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Effect of low-level laser therapy on pain resulting from orthodontic interproximal stripping: a randomized controlled trial

  • 期刊论文

  • 发表日期：

    2025年4月8日

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  • Amin Golshah,
  • Fatemeh Azizi,
  • Soraya Seifodini,
  • Amanj Kefee Najmuldeen,
  • Nafiseh Nikkerdar

摘要

Purpose

This study evaluated the effect of low-level laser therapy (LLLT) on pain resulting from interproximal stripping in orthodontic patients.

Methods

In this double-blind, parallel-group randomized controlled trial, 21 orthodontic patients requiring interproximal stripping were randomly assigned to three groups (n = 7 each): LLLT (940 nm laser, 32 J/cm², 180 s, applied to labial and lingual surfaces of the anterior mandible), placebo (laser in off mode), and control (no laser). Pain levels were assessed using a visual analog scale (VAS) at 3, 24, and 72 h post-treatment. Data were analyzed using SPSS with an alpha level of 0.05.

Results

At 3 h post-treatment, patients in the LLLT group reported no pain (VAS = 0 at all time points). The placebo group experienced mild pain (VAS = 0.43 ± 0.53), while the control group reported significantly higher pain levels (VAS = 2.29 ± 0.76). Pain scores in the control group continued to decrease over time (VAS = 1.14 ± 0.90 at 3 h, 0.57 ± 0.79 at 24 h, and 0.14 ± 0.38 at 72 h). A significant difference in pain scores was observed among the three groups after adjusting for demographics and oral hygiene (P < 0.001). The LLLT and placebo groups had significantly lower mean pain scores compared to the control group (P < 0.001), but there was no significant difference between the LLLT and placebo groups (P = 1.00).

Conclusion

LLLT effectively reduced pain associated with interproximal stripping in orthodontic patients. However, the placebo treatment yielded similar pain relief, suggesting a potential placebo effect.

Clinical Trial Registration

Iranian Registry of Clinical Trials (IRCT20130812014333N192).