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<p> Plant virus outbreaks pose a major threat to global crop production, requiring durable and sustainable resistance strategies. This perspective, arising from the 57th meeting of the DPG Working Group “Viruskrankheiten der Pflanzen”, highlights advances in resistance mechanisms, breeding, and diagnostics. We emphasize the integration of classical breeding with modern tools such as GWAS, marker-assisted selection, CRISPR/Cas editing, RNA interference, and epigenetic approaches. High-throughput sequencing and bioinformatics are transforming diagnostics and surveillance, while breeder perspectives stress agronomic and regulatory integration. Together, these developments point to interdisciplinary pathways for achieving resilient, virus-resistant cultivars to support sustainable agriculture.</p>

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Towards durable plant virus resistance: a perspective on mechanisms, breeding and diagnostic innovations

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年12月15日

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  • Katia Schütze,
  • Ullrich Dubiella,
  • Annette Niehl,
  • Björn Krenz

摘要

Plant virus outbreaks pose a major threat to global crop production, requiring durable and sustainable resistance strategies. This perspective, arising from the 57th meeting of the DPG Working Group “Viruskrankheiten der Pflanzen”, highlights advances in resistance mechanisms, breeding, and diagnostics. We emphasize the integration of classical breeding with modern tools such as GWAS, marker-assisted selection, CRISPR/Cas editing, RNA interference, and epigenetic approaches. High-throughput sequencing and bioinformatics are transforming diagnostics and surveillance, while breeder perspectives stress agronomic and regulatory integration. Together, these developments point to interdisciplinary pathways for achieving resilient, virus-resistant cultivars to support sustainable agriculture.