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<p>Marine bioactive compounds, derived from seaweeds, offer extensive therapeutic potentials. In this context, the aim of this study was to explore the biological properties of invasive red seaweed <i>Grateloupia turuturu</i> crude extract collected from the coastal region of Tipaza. Total polyphenol and flavonoid contents were first determined in the extracts, which were subsequently evaluated for their antioxidant, antibacterial, anti-inflammatory, and anticancer activities. The extracts demonstrated strong antioxidant activity in various assays, including DPPH, β-carotene bleaching, ABTS, FRAP, and hydroxyl radical scavenging tests. Significant antimicrobial activity was observed against a range of pathogenic microorganisms with particularly marked antifungal efficacy. Also, the anti-inflammatory potential was confirmed by the extract’s ability to inhibit protein denaturation in a dose-dependent manner. Furthermore, a significant reduction in the viability of breast cancer cells MCF7 was induced by the extract of <i>Grateloupia turuturu</i>, indicating promising anticancer potential. In summary, <i>Grateloupia turuturu</i> was identified as promising sources of bioactive compounds.</p>

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Evaluation of Bioactive Compounds and Biological Potentials of Red Seaweed Grateloupia turuturu

  • 期刊论文

  • 发表日期：

    2026年1月10日

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  • Mohamed Abidi,
  • Aicha Debib,
  • Borhane Eddine C. Ziani,
  • Soumaya Menadi,
  • Liza Saher,
  • Hiba Hadj Mehdi,
  • Assia Fodili,
  • Ercan Cacan

摘要

Marine bioactive compounds, derived from seaweeds, offer extensive therapeutic potentials. In this context, the aim of this study was to explore the biological properties of invasive red seaweed Grateloupia turuturu crude extract collected from the coastal region of Tipaza. Total polyphenol and flavonoid contents were first determined in the extracts, which were subsequently evaluated for their antioxidant, antibacterial, anti-inflammatory, and anticancer activities. The extracts demonstrated strong antioxidant activity in various assays, including DPPH, β-carotene bleaching, ABTS, FRAP, and hydroxyl radical scavenging tests. Significant antimicrobial activity was observed against a range of pathogenic microorganisms with particularly marked antifungal efficacy. Also, the anti-inflammatory potential was confirmed by the extract’s ability to inhibit protein denaturation in a dose-dependent manner. Furthermore, a significant reduction in the viability of breast cancer cells MCF7 was induced by the extract of Grateloupia turuturu, indicating promising anticancer potential. In summary, Grateloupia turuturu was identified as promising sources of bioactive compounds.