<p>Nowadays, cosmetics formulated with natural molecules are highly valued for being safer and more environmentally sustainable than synthetic products. This study reports the formulation of four cosmetic products: Scrub (P1), Hydra Cream (P2), Serum (P3), and Shampoo (P4), enriched with a plant extract from <i>Artemisia campestris</i> L. The extract showed high polyphenol (272.94&#xa0;mg GAE/g DW) and flavonoid (118.52&#xa0;mg QE/g DW) contents, with strong antioxidant activity (IC₅₀ = 0.36 mg.mL^− 1). HPLC analysis identified naringenin (36.29%), quercetin (28.78%), and protocatechuic acid (17.59%) as major constituents. Regarding the formulation products, P1 exhibited the highest phenolic content (77.11&#xa0;mg GAE/g), whereas P4 showed the lowest (11.19&#xa0;mg GAE/g). Due to limited solubility, only P1 and P3 demonstrated moderate antioxidant activities, with IC₅₀ values of 48 and 59.38 mg.mL^− 1, respectively. Furthermore, the oxidative stability test revealed that P1 was the most resistant, with an induction time of 2.93&#xa0;h at 120&#xa0;°C, compared to the other formulations. Consistent with the UV–Vis analysis, P1 maintained a stable absorbance, indicating enhanced optical and chemical stability, whereas P2, P3, and P4 exhibited variable signals, suggesting that these formulations may require light protection to preserve their efficacy. Sensory evaluation of these products revealed distinct performances across visual, olfactory, tactile, and perceived effect criteria, with P2 receiving the highest overall acceptance, followed by P1, then P3, and P4. This study concluded that incorporating <i>A. campestris</i> extract into cosmetic products can serve as a natural alternative to synthetic additives, enhancing product efficacy in their intended applications, promoting human health, and supporting more sustainable and environmentally friendly practices. Graphical abstract.</p> Graphical abstract <p></p>