Scholarlink

Abstract <p>Inorganic metal nanoparticles present a powerful option for both therapeutic and photocatalytic applications, owing to their distinctive characteristics that address various challenges. Zinc oxide (ZnO) and copper oxide (CuO) nanoparticles, in particular, have been noted for their safety and efficacy in a variety of biomedical applications as well as environmental clean-up efforts. This study aims to synthesize CuO-ZnO NPs by combining copper and zinc oxides using <i>Erythrina variegata</i> aqueous leaf extract, prioritizing eco-friendly methods and minimizing environmental impact. The green-synthesized CuO-ZnO NPs exhibit a band gap of 2.441&#xa0;eV. Their crystal size is measured at 18.26&#xa0;nm, and the average&#xa0;particle size is found&#xa0;38.53&#xa0;nm, as determined by transmission electron microscopy (TEM). Additionally, these nanoparticles possess a zeta potential of -20.7&#xa0;mV. X-ray photoelectron spectroscopy (XPS) analysis verifies the elemental configuration of the CuO-ZnO NPs. In vitro, cytotoxicity tests reveal that these CuO-ZnO NPs exhibit remarkable toxicity towards HeLa cancer cells, with an IC<sub>50</sub> of 35 ± 2.3&#xa0;μg/mL, compared to healthy HEK293 kidney cells. Furthermore, the CuO-ZnO NPs show significant antibacterial action against <i>E. coli</i> and <i>S. aureus</i>. The CuO-ZnO NPs demonstrate strong photocatalytic capabilities, degrading 90% of industrial organic dyes such as methylene blue and congo red under sunlight within 150&#xa0;min. Experimental and clinical research on CuO-ZnO NPs holds the potential to revolutionize environmental and therapeutic applications.</p> Graphical Abstract <p></p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Eco-friendly synthesis of CuO-ZnO bimetallic nanoparticles via Erythrina variegata leaf extract: biological applications and photocatalytic degradation of organic dyes

  • 期刊论文

  • 发表日期：

    2025年5月15日

查看全文
  • Gouranga Dutta,
  • Sivakumar Manickam,
  • Abimanyu Sugumaran,
  • Damodharan Narayanasamy

摘要

Abstract

Inorganic metal nanoparticles present a powerful option for both therapeutic and photocatalytic applications, owing to their distinctive characteristics that address various challenges. Zinc oxide (ZnO) and copper oxide (CuO) nanoparticles, in particular, have been noted for their safety and efficacy in a variety of biomedical applications as well as environmental clean-up efforts. This study aims to synthesize CuO-ZnO NPs by combining copper and zinc oxides using Erythrina variegata aqueous leaf extract, prioritizing eco-friendly methods and minimizing environmental impact. The green-synthesized CuO-ZnO NPs exhibit a band gap of 2.441 eV. Their crystal size is measured at 18.26 nm, and the average particle size is found 38.53 nm, as determined by transmission electron microscopy (TEM). Additionally, these nanoparticles possess a zeta potential of -20.7 mV. X-ray photoelectron spectroscopy (XPS) analysis verifies the elemental configuration of the CuO-ZnO NPs. In vitro, cytotoxicity tests reveal that these CuO-ZnO NPs exhibit remarkable toxicity towards HeLa cancer cells, with an IC50 of 35 ± 2.3 μg/mL, compared to healthy HEK293 kidney cells. Furthermore, the CuO-ZnO NPs show significant antibacterial action against E. coli and S. aureus. The CuO-ZnO NPs demonstrate strong photocatalytic capabilities, degrading 90% of industrial organic dyes such as methylene blue and congo red under sunlight within 150 min. Experimental and clinical research on CuO-ZnO NPs holds the potential to revolutionize environmental and therapeutic applications.

Graphical Abstract