<p>Each year, huge quantities of solid waste from various construction and demolition wastes are generated. This waste is not recycled but is thrown directly into the environment and placed in landfills. By recycling solid waste like ceramic waste powder (CWP), this study aims to create sustainable cement grout for semi-flexible pavement applications that can withstand high traffic and severe weather conditions. Portland cement was partially replaced by CWP in varying percentages (15%, 20%, 30%, 40%, and 50%) to produce cement-based grout. The grout mixtures were tested for compressive strength and flow properties. A life cycle assessment (LCA) was also conducted to evaluate the sustainability performance of both conventional and modified grout with CWP. The mechanical test results showed that the optimal cement replacement ratio with CWP is 20%, which increased the compressive strength, skis resistance, indirect tensile strength, and tensile strength ratio by 50%, 25%, 64%, and 24%, respectively, at 28&#xa0;days of curing. Similarly, the durability test results indicated that incorporating the same CWP content at the same curing age reduced particle loss and rutting by 31% and 76%, respectively. This significant improvement in performance tests can be attributed to the high flowability of CWP, which fills all voids in the porous asphalt mixture, and its superior ability to produce a significant amount of calcium silicate hydrate (C–S–H) gel. According to the LCA results, increasing CWP cement replacement levels resulted in lower environmental impacts and improved sustainability performance for the developed grouts.</p>