Scholarlink

Background <p>Sex cord stromal tumour (SCST) is a less common ovarian neoplasm constituting around 8% of all ovarian malignancies. The commonest SCST is granulosa cell tumor. The adult subtype constitutes the majority (95%) cases in contrast to the juvenile subtype seen in only 5% of granulosa cell tumors.</p> Case presentation <p>The following report is of a juvenile granulosa cell tumor (JGCT) in a 20 years old unmarried lady, who complained of pain abdomen and irregular menstruation with passage of clots and dysmenorrhea for 2 months. Ultrasound pelvis showed enlarged right ovary with increased vascularity, possibly secondary to torsion -detorsion sequence. The relevant tumor markers, Prolactin and Beta HCG were within normal limits. MRI pelvis showed a heterogeneously enhancing solid lesion with necrotic and hemorrhagic areas in right ovary, likely suggestive of germ cell tumor. Surgical intervention, right salpingo-oophorectomy was done and ovarian mass of ~ 6 × 5 × 4 cm was resected. HPE showed features suggestive of malignant ovarian neoplasm with differentials of SCST/ germ cell tumor. IHC showed features suggestive of JGCT.</p> Conclusion <p>JGCT has nonspecific radiological features and prognosis corelates with the stage of the tumor at diagnosis which emphasizes the need for an early diagnosis.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Juvenile Granulosa Cell Ovarian Tumour- Case Study with Radio-pathological Correlation

  • 期刊论文

  • 发表日期：

    2025年12月19日

查看全文
  • K. Suprasanna,
  • Abhijeet Gourishetty,
  • Rakshatha Nayak,
  • Nikil Shetty,
  • Sahana D. Acharya

摘要

Background

Sex cord stromal tumour (SCST) is a less common ovarian neoplasm constituting around 8% of all ovarian malignancies. The commonest SCST is granulosa cell tumor. The adult subtype constitutes the majority (95%) cases in contrast to the juvenile subtype seen in only 5% of granulosa cell tumors.

Case presentation

The following report is of a juvenile granulosa cell tumor (JGCT) in a 20 years old unmarried lady, who complained of pain abdomen and irregular menstruation with passage of clots and dysmenorrhea for 2 months. Ultrasound pelvis showed enlarged right ovary with increased vascularity, possibly secondary to torsion -detorsion sequence. The relevant tumor markers, Prolactin and Beta HCG were within normal limits. MRI pelvis showed a heterogeneously enhancing solid lesion with necrotic and hemorrhagic areas in right ovary, likely suggestive of germ cell tumor. Surgical intervention, right salpingo-oophorectomy was done and ovarian mass of ~ 6 × 5 × 4 cm was resected. HPE showed features suggestive of malignant ovarian neoplasm with differentials of SCST/ germ cell tumor. IHC showed features suggestive of JGCT.

Conclusion

JGCT has nonspecific radiological features and prognosis corelates with the stage of the tumor at diagnosis which emphasizes the need for an early diagnosis.