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Background <p>Isolated bone metastasis from uterine cervical cancer is rare, with very few cases documented in the literature.</p> Purpose and method <p>We present the case of a 35-year-old woman diagnosed with FIGO Stage IIB invasive squamous cell carcinoma of the cervix, treated with chemoradiation and brachytherapy, achieving a complete clinical and radiological response. Eleven months later, a whole-body PET/CT scan identified an isolated lesion in the proximal left clavicle without evidence of other skeletal metastases. Biopsy confirmed metastatic squamous cell carcinoma.</p> Result <p>The patient received three cycles of chemotherapy before surgical resection, with good local control and no recurrence six months post-surgery.</p> Conclusion <p>This case report illustrates the interest of aggressive management of isolated bone metastasis from cervical carcinoma in a young patient.</p>

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Clavicular Metastasis from Cervical Cancer: A Case Report and Review of the Literature

  • 期刊论文

  • 发表日期：

    2025年1月20日

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  • Maroua Benlemlih,
  • Mohamed El Marjany,
  • Adil Arsalane,
  • Manale Otmani,
  • Mouhcine Hommadi,
  • Elamin Marnouche,
  • Abdelhak Maghous,
  • Amine Bazine,
  • Issam Lalya,
  • Khalid Andaloussi Saghir,
  • Khalid Hadadi,
  • Hassan Sifat

摘要

Background

Isolated bone metastasis from uterine cervical cancer is rare, with very few cases documented in the literature.

Purpose and method

We present the case of a 35-year-old woman diagnosed with FIGO Stage IIB invasive squamous cell carcinoma of the cervix, treated with chemoradiation and brachytherapy, achieving a complete clinical and radiological response. Eleven months later, a whole-body PET/CT scan identified an isolated lesion in the proximal left clavicle without evidence of other skeletal metastases. Biopsy confirmed metastatic squamous cell carcinoma.

Result

The patient received three cycles of chemotherapy before surgical resection, with good local control and no recurrence six months post-surgery.

Conclusion

This case report illustrates the interest of aggressive management of isolated bone metastasis from cervical carcinoma in a young patient.