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<p>Gold (Au) nanoparticles (NPs) have been identified as essential for orchestrating an enhanced efficacy of 3D-printed scaffolds in biomedical applications. This review examines the potential of Au NPs integrated with 3D printing technologies, with a focus on their applications in cardiac, bone, and muscle tissue engineering. The integration of Au NPs into 3D printed scaffolds offers a transformative approach to enhancing scaffold performance by leveraging the physicochemical properties of Au NPs, such as their high surface-to-volume ratio, tunable optical properties, and biocompatibility. Recent advancements highlight the potential of Au NP-based 3D scaffolds in tissue regeneration, as they enhance mechanical strength, improve electrical conductivity, and facilitate controlled drug release. Additionally, these scaffolds have a positive influence on cellular activities and imaging capabilities, making them highly relevant in modern medical applications. This review explores the synergistic benefits of combining Au NPs with 3D printing, paving the way for innovative advancements in personalized medicine and therapeutic strategies.</p>

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Advancements in Gold Nanoparticle-Infused 3D-printed Scaffolds for Cardiac, Muscle, and Bone Tissue Engineering

  • 期刊论文

  • 发表日期：

    2026年1月5日

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  • Salsabeel Amin Kabli,
  • Muheeb Rafiq,
  • Ibtisam Hamid,
  • Sumayah-Shakil Wani,
  • Rumysa Saleem Khan,
  • Anjum Hamid Rather,
  • Rabia Hamid,
  • Touseef Amna,
  • M. Shamshi Hassan,
  • Faheem A. Sheikh

摘要

Gold (Au) nanoparticles (NPs) have been identified as essential for orchestrating an enhanced efficacy of 3D-printed scaffolds in biomedical applications. This review examines the potential of Au NPs integrated with 3D printing technologies, with a focus on their applications in cardiac, bone, and muscle tissue engineering. The integration of Au NPs into 3D printed scaffolds offers a transformative approach to enhancing scaffold performance by leveraging the physicochemical properties of Au NPs, such as their high surface-to-volume ratio, tunable optical properties, and biocompatibility. Recent advancements highlight the potential of Au NP-based 3D scaffolds in tissue regeneration, as they enhance mechanical strength, improve electrical conductivity, and facilitate controlled drug release. Additionally, these scaffolds have a positive influence on cellular activities and imaging capabilities, making them highly relevant in modern medical applications. This review explores the synergistic benefits of combining Au NPs with 3D printing, paving the way for innovative advancements in personalized medicine and therapeutic strategies.