<p>Diabetic wounds exhibit incomplete and delayed healing processes, which exposes patient conditions that are highly infectious. With increased understanding of the molecular principles behind these disorders, new medical technologies are entering market for traditional wound treatment. By incorporating both bioactive molecules and non-bioactive materials, nanoparticles and hydrogels aid in the healing of diabetic wounds. Nanotherapeutics, nanoparticles (NPs), nanofibers, nanohydrogels, and nanoscale scaffolds are nanotechnology-based systems that have garnered interest for their potential to enhance the understanding of biological environments and improve wound healing treatment strategies. These nanotechnology platforms can proficiently address the issues associated with drug toxicity, traditional treatment modalities, and the intricate characteristics of wound sites. This review discusses recent advancements in nanomaterials and biomaterials for wound healing in diabetes.</p> Graphical Abstract <p></p>