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Purpose <p>Abnormal mechanical conditions have an extremely important influence in the repair of cartilage defects and the development of arthritis, and therefore the mechanical behavior of articular cartilage defects as well as after repair needs to be clarified. To investigate the mechanical behavior of the contact region after total knee cartilage defects and repairs under compression loading.</p> Methods <p>Under physiological load, the whole and local pressure distribution of defect including intact cartilage as well as repaired cartilages in pig knee-joint were measured by establishing the defective and repaired articular cartilage models, using full-thickness defect with the shape of round, square, triangle and trapezoid on femoral cartilage and repairing defect by artificial cartilage with high elastic modulus and low.</p> Results <p>The pressures of contact area redistributed in defect cartilage and repaired under physiological load. Defects with various shapes produced stress concentrations at the edge, which enhanced 3.4 or 4.66 times of normal stress, or even 6.21 times. The defects including repairing with soft artificial cartilage caused abnormal pressure distribution in the contact area deviating from that in the intact group. Stiff artificial cartilage with high compressive modulus bore relatively high pressure in the repaired area, and was close to the level of natural cartilage, and the phenomenon of stress concentration at the edge was almost eliminated, but the pressure distribution in the whole contact area was still slightly different from that in the intact group. In addition, the peak position of pressure changed in the defect as well as repaired group with respect to the intact group.</p> Conclusion <p>The cartilage defect as well as post-repair changed the distribution of contact pressure in the total knee joint. Our findings can provide evidence for better repair and treatment of articular cartilage injury.</p>

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Stress Behaviors of Cartilage with Defect and After Repair in Total Knee Under Compression Loading

  • 期刊论文

  • 发表日期：

    2025年11月15日

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  • Xianglong Lin,
  • Shilei Wang,
  • Bolun Liu,
  • Lilan Gao,
  • Linwei Lyu,
  • Chunqiu Zhang

摘要

Purpose

Abnormal mechanical conditions have an extremely important influence in the repair of cartilage defects and the development of arthritis, and therefore the mechanical behavior of articular cartilage defects as well as after repair needs to be clarified. To investigate the mechanical behavior of the contact region after total knee cartilage defects and repairs under compression loading.

Methods

Under physiological load, the whole and local pressure distribution of defect including intact cartilage as well as repaired cartilages in pig knee-joint were measured by establishing the defective and repaired articular cartilage models, using full-thickness defect with the shape of round, square, triangle and trapezoid on femoral cartilage and repairing defect by artificial cartilage with high elastic modulus and low.

Results

The pressures of contact area redistributed in defect cartilage and repaired under physiological load. Defects with various shapes produced stress concentrations at the edge, which enhanced 3.4 or 4.66 times of normal stress, or even 6.21 times. The defects including repairing with soft artificial cartilage caused abnormal pressure distribution in the contact area deviating from that in the intact group. Stiff artificial cartilage with high compressive modulus bore relatively high pressure in the repaired area, and was close to the level of natural cartilage, and the phenomenon of stress concentration at the edge was almost eliminated, but the pressure distribution in the whole contact area was still slightly different from that in the intact group. In addition, the peak position of pressure changed in the defect as well as repaired group with respect to the intact group.

Conclusion

The cartilage defect as well as post-repair changed the distribution of contact pressure in the total knee joint. Our findings can provide evidence for better repair and treatment of articular cartilage injury.