<p>Dual-atom catalysts (DACs) that originate as an outgrowth of single-atom catalysts (SACs) have recently captured considerable attention. DACs that perfectly inherit the advantages of SACs, namely, the maximum atomic utilization efficiency, however, are supposed to show better catalytic performance than simple SACs owing to their higher metal loadings, flexible dual active sites in proximity, and unique electronic properties. Hence, in this review, we summarize recent progress of DACs from the perspective of synthetic methods, unique electronic properties, and their applications in a series of energy-related electrocatalytic reactions. First, major approaches that are comprised of pyrolysis, wet-chemistry, atomic layer deposition, chemical vapor deposition, and ball milling are overviewed for the fabrication of DACs. Second, unique electronic properties between dual-atom sites in DACs that consist of charge transfer, energy band structure, and spin state are further described. Then, the applications of DACs in various energy-related electrocatalysis are discussed to elucidate the structure-performance relationship and understand the reaction mechanism. Finally, a conclusion of this review and insights into the challenges and prospects pertaining to this field are also highlighted.</p>