Scholarlink

<p>This study evaluates the mechanical, corrosion, biological, and deployment behavior of zinc-based alloys. The alloys were fabricated using powder metallurgy, with the aim of developing materials suitable for bioresorbable cardiovascular stents. Microstructural analysis revealed that Zn–4Cu formed intermetallic compounds, notably CuZn<sub>5</sub>, whereas Zn–4Ag contained ε-AgZn<sub>3</sub> dendrites within a primary η-Zn matrix. The experimental results demonstrated that alloying improved both the mechanical strength and density of the material. Zn–4Ag exhibited the highest hardness (78 Hv), while Zn–4Cu showed superior yield strength (175.5&#xa0;MPa) and compressive strength (181.7&#xa0;MPa). Electrochemical corrosion analysis in Ringer’s solution indicated that Zn–4Ag exhibited the lowest corrosion rate (0.0192 mmpy). Biological assessments demonstrated excellent biocompatibility, with Zn–4Cu showing the highest cell viability and notable antibacterial activity against E. coli. Finite element analysis of stent deployment revealed comparable expansion behavior for both alloys, with maximum von Mises stresses of 263&#xa0;MPa for Zn–4Cu and 273&#xa0;MPa for Zn–4Ag concentrated at the crown apices. These findings highlight the potential of Zn–4Cu and Zn–4Ag alloys for next-generation bioresorbable stents, offering a balanced combination of mechanical strength, corrosion resistance, and biocompatibility.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Experimental Investigation and Computational Modeling of Zinc-Based Alloys for Bioresorbable Cardiovascular Stents

  • 期刊论文

  • 发表日期：

    2026年2月4日

查看全文
  • Khursheed Ahmad Sheikh,
  • Mohammad Irfan Hajam,
  • Mohammad Mohsin Khan,
  • Anas Ali

摘要

This study evaluates the mechanical, corrosion, biological, and deployment behavior of zinc-based alloys. The alloys were fabricated using powder metallurgy, with the aim of developing materials suitable for bioresorbable cardiovascular stents. Microstructural analysis revealed that Zn–4Cu formed intermetallic compounds, notably CuZn5, whereas Zn–4Ag contained ε-AgZn3 dendrites within a primary η-Zn matrix. The experimental results demonstrated that alloying improved both the mechanical strength and density of the material. Zn–4Ag exhibited the highest hardness (78 Hv), while Zn–4Cu showed superior yield strength (175.5 MPa) and compressive strength (181.7 MPa). Electrochemical corrosion analysis in Ringer’s solution indicated that Zn–4Ag exhibited the lowest corrosion rate (0.0192 mmpy). Biological assessments demonstrated excellent biocompatibility, with Zn–4Cu showing the highest cell viability and notable antibacterial activity against E. coli. Finite element analysis of stent deployment revealed comparable expansion behavior for both alloys, with maximum von Mises stresses of 263 MPa for Zn–4Cu and 273 MPa for Zn–4Ag concentrated at the crown apices. These findings highlight the potential of Zn–4Cu and Zn–4Ag alloys for next-generation bioresorbable stents, offering a balanced combination of mechanical strength, corrosion resistance, and biocompatibility.