<p>Differential reinforcement of other behavior (DRO) is a reinforcement schedule used in behavior analytic procedures aimed at decreasing various forms of behavior. DRO commonly includes reinforcement and extinction components; a reinforcer is delivered on an interval-based schedule dependent on the omission of a target behavior, and the reinforcer is withheld following the occurrence of the target behavior (i.e., extinction). A DRO schedule can be implemented without extinction, but previous research has shown limited utility of this tactic. Research has shown that another form of differential reinforcement, differential reinforcement of alternative behavior, can decrease behavior in the absence of extinction with asymmetrical reinforcers (i.e., differentially manipulating parameters such as magnitude, immediacy, and quality). This experiment examined the effects of DRO with and without asymmetrical magnitude of reinforcement for the omission and emission of the target response. Target responding was reinforced during baseline. In one treatment condition, a relatively higher magnitude of points was delivered contingent on the absence of the target behavior (DRO without extinction). In another condition, the magnitude of points for engaging in the target behavior and omitting the target behavior was symmetrical (i.e., the same number of points). In the final condition, DRO was applied with extinction. The results do not support the use of DRO without extinction using an asymmetrical magnitude of reinforcement.</p>