Purpose of Review <p>This review explores the factors contributing to well-being among acute care surgeons and the role of leadership in fostering a supportive environment. It discusses the unique challenges faced by acute care surgeons and highlights the importance of addressing burnout and promoting wellness within the profession to ensure a sustainable future.</p> Recent Findings <p>Recent studies have shown that burnout rates among surgeons, particularly acute care surgeons, continue to increase despite growing awareness of the issue. Culture and leadership are an important but understudied contributors to foster <Emphasis Type="BoldUnderline">or</Emphasis> worsen overall well-being. Junior attendings experience significant stress during the transition from trainee to increased responsibility, requiring direct support and mentorship, while mid-career and senior attendings prioritize leadership coaching and career development for their well-being. The "second victim" phenomenon, prevalent in over half of surgeons, leads to short and long-term psychological effects following adverse events or mistakes, emphasizing the importance of peer support programs and resources from professional organizations. Finally, female surgeons face unique challenges related to pregnancy and the port-partum period, highlighting the need for tangible support and accommodations.</p> Summary <p>Overall health of acute care surgeons requires intentional awareness and effort from leadership locally and nationally. This includes objectives measures of schedule and compensation transparency as well as the emotion impact of adverse events. Leaders must prioritize the personal and family needs of surgeons. By addressing these factors and promoting a supportive environment, we can ensure the long-term success of individual programs and the specialty of acute care surgery.</p>