For every nuclear \({\mathbb {Z}}_\ell \) -algebra \(\Lambda \) and every small v-stack X on perfectoid spaces, we construct an \(\infty \) -category \(\mathcal {D}_{\textrm{nuc}}(X,\Lambda )\) of nuclear (i.e., “ind-Banach”) \(\Lambda \) -modules on X. We then construct a full 6-functor formalism for these sheaves, generalizing the étale 6-functor formalism for \(\Lambda = \mathbb {F}_\ell \) . Prominent choices for \(\Lambda \) are \({\mathbb {Z}}_\ell \) , \(\mathbb {Q}_\ell \) and \(\overline{\mathbb {Q}_\ell }\) . We also provide and study an abstract notion of ULA sheaves in this setting, whose definition and basic properties can be carried over to any 6-functor formalism. Applied to classifying stacks, we obtain a robust theory of nuclear representations, i.e., continuous representations on filtered colimits of Banach spaces.