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Purpose of Review <p>In this review we summarise relevant, replicated and exciting findings from twin studies focusing on the topic of sleep.</p> Recent Findings <p>Here we report that: a) most sleep-related traits and disorders are substantially influenced by genetic factors; b) shared environmental factors do not explain a substantial proportion of the variance of sleep variables except during early in life; c) genetic and environmental influences on sleep and sleep disorders remain relatively stable from adolescence onwards; d) the relative role of genetic and environmental factors explaining individual differences for sleep quality, sleep duration and insomnia are similar for men and women; e) sleep-related variables/ sleep disorders are genetically related to major mental health traits; f) sleep quality has significant bidirectional associations with general health-related variables; and g) data from twin studies can make unique contributions to testing and progressing models and theories of insomnia (including by testing gene-environment interplay).</p> Summary <p>Twin studies have invigorated sleep research during the decades and we anticipate the publication of many more important studies using these methodologies.</p>

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A Narrative Review of Twin Study Contributions to the Understanding of Sleep and Sleep Disorders

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年5月17日

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  • Juan J. Madrid-Valero,
  • Juan R. Ordoñana,
  • Alice M. Gregory

摘要

Purpose of Review

In this review we summarise relevant, replicated and exciting findings from twin studies focusing on the topic of sleep.

Recent Findings

Here we report that: a) most sleep-related traits and disorders are substantially influenced by genetic factors; b) shared environmental factors do not explain a substantial proportion of the variance of sleep variables except during early in life; c) genetic and environmental influences on sleep and sleep disorders remain relatively stable from adolescence onwards; d) the relative role of genetic and environmental factors explaining individual differences for sleep quality, sleep duration and insomnia are similar for men and women; e) sleep-related variables/ sleep disorders are genetically related to major mental health traits; f) sleep quality has significant bidirectional associations with general health-related variables; and g) data from twin studies can make unique contributions to testing and progressing models and theories of insomnia (including by testing gene-environment interplay).

Summary

Twin studies have invigorated sleep research during the decades and we anticipate the publication of many more important studies using these methodologies.