Scholarlink

Background <p>While significant sociodemographic disparities in the burden of chronic kidney disease (CKD) are well established, less is known about how area-level socioeconomic status interacts with these disparities.</p> Methods <p>This study used data from the Centers for Disease Control and Prevention Wide-Ranging Online Database for Epidemiologic Research (CDC WONDER) Underlying Cause of Death Database to identify deaths from CKD among people aged 45 and older in the United States from 1999–2020. We used county-level Social Vulnerability Index data to examine the relationship between Social Vulnerability Index and CKD-associated mortality for the overall population and for sociodemographic subgroups.</p> Results <p>The age-adjusted mortality rate for the overall population was 73.56 (95% CI 67.74–79.39). Mortality from CKD was significantly higher in the 4th quartile of Social Vulnerability Index, representing the most vulnerable areas (age-adjusted mortality rate = 81.39, 95% CI 75.77–87.00), compared to the 1st quartile, representing the least vulnerable areas (age-adjusted mortality rate = 66.07, 95% CI 59.02–73.12). For both the overall population and all sociodemographic subgroups, higher Social Vulnerability Index was associated with a higher risk of CKD-associated mortality. Within each Social Vulnerability Index quartile, Black Americans and males had higher CKD-associated mortality than White Americans and females, respectively.</p> Conclusion <p>The burden of CKD-associated mortality in the United States is rising, with people living in more socially vulnerable counties facing a higher risk of CKD death. Racial disparities in CKD-associated mortality persist even within counties of similar social vulnerability, indicating the urgent need to address these health disparities.</p> Graphical abstract <p></p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Social vulnerability and chronic kidney disease-associated mortality in the United States: 1999–2020

  • 期刊论文

  • 发表日期：

    2025年8月4日

查看全文
  • Benjamin Grobman,
  • Arian Mansur,
  • Christine Y. Lu

摘要

Background

While significant sociodemographic disparities in the burden of chronic kidney disease (CKD) are well established, less is known about how area-level socioeconomic status interacts with these disparities.

Methods

This study used data from the Centers for Disease Control and Prevention Wide-Ranging Online Database for Epidemiologic Research (CDC WONDER) Underlying Cause of Death Database to identify deaths from CKD among people aged 45 and older in the United States from 1999–2020. We used county-level Social Vulnerability Index data to examine the relationship between Social Vulnerability Index and CKD-associated mortality for the overall population and for sociodemographic subgroups.

Results

The age-adjusted mortality rate for the overall population was 73.56 (95% CI 67.74–79.39). Mortality from CKD was significantly higher in the 4th quartile of Social Vulnerability Index, representing the most vulnerable areas (age-adjusted mortality rate = 81.39, 95% CI 75.77–87.00), compared to the 1st quartile, representing the least vulnerable areas (age-adjusted mortality rate = 66.07, 95% CI 59.02–73.12). For both the overall population and all sociodemographic subgroups, higher Social Vulnerability Index was associated with a higher risk of CKD-associated mortality. Within each Social Vulnerability Index quartile, Black Americans and males had higher CKD-associated mortality than White Americans and females, respectively.

Conclusion

The burden of CKD-associated mortality in the United States is rising, with people living in more socially vulnerable counties facing a higher risk of CKD death. Racial disparities in CKD-associated mortality persist even within counties of similar social vulnerability, indicating the urgent need to address these health disparities.

Graphical abstract