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<p>Craniopharyngiomas are associated with several cardiometabolic comorbidities, often severe and multifactorial in nature, contributing to increased cardiovascular mortality. Beyond hypothalamic obesity, insulin resistance, type 2 diabetes, atherogenic dyslipidaemia, hypertension, hepatic steatosis and fibrosis, as well as structural cardiac abnormalities, are frequently observed. This review examines these complications in terms of prevalence, pathogenesis, treatment response, and emerging therapeutic options, highlighting the need for a proactive and multidisciplinary follow-up.</p>

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Salute cardiometabolica nei pazienti con craniofaringioma: oltre l’obesità ipotalamica

  • 期刊论文

  • 发表日期：

    2026年3月23日

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  • Lorenzo Cerroni,
  • Ludovica Vincenzi,
  • Dario De Alcubierre

摘要

Craniopharyngiomas are associated with several cardiometabolic comorbidities, often severe and multifactorial in nature, contributing to increased cardiovascular mortality. Beyond hypothalamic obesity, insulin resistance, type 2 diabetes, atherogenic dyslipidaemia, hypertension, hepatic steatosis and fibrosis, as well as structural cardiac abnormalities, are frequently observed. This review examines these complications in terms of prevalence, pathogenesis, treatment response, and emerging therapeutic options, highlighting the need for a proactive and multidisciplinary follow-up.