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<p>Prostate cancer (PCa) is among the most common malignancies in men. Obesity, insulin resistance, and hyperglycaemia contribute to its progression. On the other hand, some therapies used for PCa can negatively impact metabolic health. Emerging evidence suggests that the ketogenic diet may enhance treatment response. Preclinical data are promising, while clinical evidence remains preliminary. This is an experimental strategy requiring careful supervision.</p>

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Diete chetogeniche e a basso contenuto di carboidrati nel cancro alla prostata: aspetti metabolici, studi preclinici e prospettive cliniche emergenti

  • 期刊论文

  • 发表日期：

    2026年1月12日

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  • Silvia Manfrini,
  • Andrea Malgeri,
  • Carmine Mone,
  • Ludovica Di Francesco,
  • Giulia Pecora,
  • Rossella Mazzilli,
  • Manon Yeganeh Khazrai,
  • Antongiulio Faggiano

摘要

Prostate cancer (PCa) is among the most common malignancies in men. Obesity, insulin resistance, and hyperglycaemia contribute to its progression. On the other hand, some therapies used for PCa can negatively impact metabolic health. Emerging evidence suggests that the ketogenic diet may enhance treatment response. Preclinical data are promising, while clinical evidence remains preliminary. This is an experimental strategy requiring careful supervision.