Scholarlink

<p>Medullary thyroid carcinoma (MTC) is a malignant tumour arising from the parafollicular C cells of the thyroid. It can occur in sporadic or hereditary forms, and surgery is the primary treatment. Ultrasound examination and, in selected cases, anatomical imaging procedures are adopted to stage the disease before primary surgery, while various anatomical/morphological and functional/molecular imaging procedures can be adopted to detect persistent/recurrent disease. Positron-emitting radiopharmaceuticals, including fluorine-18 fluorodeoxyglucose (18F-FDG), fluorine-18 dihydroxyphenylalanine (18F-FDOPA), and gallium-68-labeled somatostatin analogues (68Ga-SSA) have been shown to be useful in detecting MTC relapse/metastasis. This review illustrates the main radiopharmaceuticals for positron imaging of MTC and provides practical indications for rational clinical use.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Diagnostica medico nucleare del carcinoma midollare tiroideo

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年2月27日

查看全文
  • Luca Giovanella

摘要

Medullary thyroid carcinoma (MTC) is a malignant tumour arising from the parafollicular C cells of the thyroid. It can occur in sporadic or hereditary forms, and surgery is the primary treatment. Ultrasound examination and, in selected cases, anatomical imaging procedures are adopted to stage the disease before primary surgery, while various anatomical/morphological and functional/molecular imaging procedures can be adopted to detect persistent/recurrent disease. Positron-emitting radiopharmaceuticals, including fluorine-18 fluorodeoxyglucose (18F-FDG), fluorine-18 dihydroxyphenylalanine (18F-FDOPA), and gallium-68-labeled somatostatin analogues (68Ga-SSA) have been shown to be useful in detecting MTC relapse/metastasis. This review illustrates the main radiopharmaceuticals for positron imaging of MTC and provides practical indications for rational clinical use.