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Background <p>Mild cognitive impairment (MCI) and dementia represent significant global health challenges requiring innovative intervention approaches. Computerized cognitive training (CCT) offers promising alternatives to traditional face-to-face interventions, providing flexibility and personalized care for individuals with cognitive disorders.</p> Aims <p>This study evaluated the usability of INFORMA, a novel software platform based on Cognitive Activation Therapy (CAT), for delivering telerehabilitation to participants with MCI and mild-to-moderate dementia.</p> Methods <p>A prospective, non-interventional multicenter study enrolled 241 participants (MMSE 20–30, CDR 0.5-1) from 12 Italian Centers for Cognitive Disorders and Dementia. Participants engaged in an 8-week tablet-based telerehabilitation program with weekly supervision. Usability was assessed using the System Usability Scale (SUS), Task Completion Rate (TCR), and Relative Task Completion Time (R-TCT), supplemented by participant and caregiver questionnaires.</p> Results <p>Of 219 completing participants (mean age 73.5 years), the mean SUS score was 82.0 (95% CI: 80.3–83.8), with 84% exceeding the usability threshold (SUS score &gt; 68). Mean TCR reached 97.8%, while 70.3% demonstrated improved R-TCT. Higher SUS scores correlated with education and MMSE scores but decreased with age. Satisfaction ratings exceeded 87% for participants and 95% for caregivers.</p> Discussion <p>INFORMA demonstrated high usability across all educational and cognitive levels, with the hybrid model combining automated exercises and professional supervision being well-received.</p> Conclusions <p>INFORMA showed significant promise as a user-friendly computerized cognitive stimulation tool, supporting its potential efficacy for MCI and dementia interventions and warranting further therapeutic efficacy studies.</p>

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Usability and feasibility of INFORMA platform for computerized cognitive stimulation in mild cognitive impairment and early dementia: an 8-week multicenter study

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年3月13日

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  • Cristina Basso,
  • Andrea Zanella,
  • Marco Simoni,
  • Carlo Fantozzi,
  • Donata Gollin,
  • Cristina Ruaro,
  • Silvia Tiozzo Netti,
  • Alessandra Zapparoli,
  • Roberta Padoan,
  • Maurizio Gallucci,
  • Livia Gallo,
  • Luca Valentinis,
  • Moira Ceci,
  • Pierluigi Dal Santo,
  • Anna Ceccon,
  • Samantha Pradelli,
  • Michela Marcon,
  • Laura De Togni,
  • Anna Maria Musso,
  • Antonino Riolo,
  • Giuseppe Gagni,
  • Carlo Gabelli,
  • Pierangelo Spano

摘要

Background

Mild cognitive impairment (MCI) and dementia represent significant global health challenges requiring innovative intervention approaches. Computerized cognitive training (CCT) offers promising alternatives to traditional face-to-face interventions, providing flexibility and personalized care for individuals with cognitive disorders.

Aims

This study evaluated the usability of INFORMA, a novel software platform based on Cognitive Activation Therapy (CAT), for delivering telerehabilitation to participants with MCI and mild-to-moderate dementia.

Methods

A prospective, non-interventional multicenter study enrolled 241 participants (MMSE 20–30, CDR 0.5-1) from 12 Italian Centers for Cognitive Disorders and Dementia. Participants engaged in an 8-week tablet-based telerehabilitation program with weekly supervision. Usability was assessed using the System Usability Scale (SUS), Task Completion Rate (TCR), and Relative Task Completion Time (R-TCT), supplemented by participant and caregiver questionnaires.

Results

Of 219 completing participants (mean age 73.5 years), the mean SUS score was 82.0 (95% CI: 80.3–83.8), with 84% exceeding the usability threshold (SUS score > 68). Mean TCR reached 97.8%, while 70.3% demonstrated improved R-TCT. Higher SUS scores correlated with education and MMSE scores but decreased with age. Satisfaction ratings exceeded 87% for participants and 95% for caregivers.

Discussion

INFORMA demonstrated high usability across all educational and cognitive levels, with the hybrid model combining automated exercises and professional supervision being well-received.

Conclusions

INFORMA showed significant promise as a user-friendly computerized cognitive stimulation tool, supporting its potential efficacy for MCI and dementia interventions and warranting further therapeutic efficacy studies.